Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001643 | 0.77 | LMNA (0.46) | PDK2RXFP1CTSSLMNAGAA | |
| SCHEMBL696461 | 0.77 | P2RX1 (0.44) | PDK2PDK1PDK3PDK4RXFP1 | |
| SCHEMBL24445835 | 0.77 | THRB (0.47) | PDK2PDK1PDK3PDK4RXFP1 | |
| SCHEMBL7784256 | 0.75 | P2RX1 (0.43) | PDK2PDK1PDK3PDK4RXFP1 | |
| SCHEMBL27500099 | 0.74 | LMNA (0.43) | ACHEKMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL7787354 | 0.72 | SMN1; SMN2 (0.47) | RXFP1KMT2AMAPTHTTL3MBTL1 | |
| SCHEMBL29945766 | 0.71 | CYP1A2 (0.43) | PDK2PDK1PDK3PDK4P2RX7 | |
| SCHEMBL23525879 | 0.71 | CYP1A2 (0.43) | PDK2PDK1PDK3PDK4P2RX7 | |
| SCHEMBL9524633 | 0.68 | CTSS (0.56) | P2RX7CTSSLMNAGAATAS2R14 | |
| SCHEMBL30562236 | 0.68 | CTSS (0.56) | P2RX7CTSSLMNAGAATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642273-B2 | Ligand sensing fluorescent acetylcholinesterase for detection of organophosphate activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-02-04 | — | — | US | disclosed |
| US-20050089926-A1 | Ligand sensing fluorescent acetylcholinesterase for detection of organophosphate activity | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-04-28 | — | — | US | disclosed |
| WO-2003089599-A2 | LIGAND SENSING FLUORESCENT ACETYLCHOLINESTERASE FOR DETECTION OF ORGANOPHOSPHATE ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-10-30 | — | — | WO | disclosed |