Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 12/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631425 | 0.87 | AVPR1A (0.51) | AVPR1AGRIN1GRIN2B | |
| SCHEMBL30407649 | 0.87 | AVPR1A (0.51) | AVPR1AGRIN1GRIN2B | |
| SCHEMBL6346561 | 0.79 | SIGMAR1 (0.55) | AVPR1A | |
| SCHEMBL9615977 | 0.72 | SIGMAR1 (0.54) | AVPR1A | |
| SCHEMBL16546758 | 0.70 | SIGMAR1 (0.47) | AVPR1A | |
| SCHEMBL29790950 | 0.69 | SIGMAR1 (0.49) | AVPR1A | |
| SCHEMBL19839273 | 0.69 | SIGMAR1 (0.41) | AVPR1A | |
| SCHEMBL30389740 | 0.67 | SIGMAR1 (0.50) | — | |
| SCHEMBL11328335 | 0.67 | SIGMAR1 (0.50) | — | |
| SCHEMBL6819933 | 0.67 | AVPR1A (0.46) | AVPR1AGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261327-A1 | 2-(Bicyclo)alkylamino-derivatives as mediatores of chronic pain and inflammation | MERCK & CO., INC. | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261327-A1 | 2-(Bicyclo)alkylamino-derivatives as mediatores of chronic pain and inflammation | BDKRB1, BDKRB2, LTB4R2 | AVPR1A 157/4885GRIN1 372/4885GRIN2B 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.