SCHEMBL6356364

SCHEMBL6356364

C=C(CCCCCO)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.48
FFAR1 O14842 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
KDM4E B2RXH2 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.38
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
CAMK2A Q9UQM7 1/20 0.35
LMNA P02545 4/20 0.32
TSHR P16473 2/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 2/20 0.31
PLG P00747 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442127 1.00 GPR84 (0.48) GPR84FFAR1FFAR4KDM4ESMN1; SMN2
SCHEMBL446745 0.98 GPR84 (0.44) GPR84FFAR1FFAR4KDM4ESMN1; SMN2
SCHEMBL36684 0.90
SCHEMBL17672227 0.90 LMNA (0.38) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL435733 0.90 LMNA (0.38) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL730324 0.90 LMNA (0.38) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL1858134 0.90 LMNA (0.38) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL732893 0.90 LMNA (0.38) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL1865622 0.90 LMNA (0.38) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL1862317 0.90 LMNA (0.38) GPR84FFAR1FFAR4LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1591462-A2 Temperature-responsive polymer compound and process for producing the same Amersham Biosciences KK (JP) 2005-11-02 EP disclosed
US-6956077-B1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK (JP) 2005-10-18 US disclosed
US-20050224415-A1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK 2005-10-13 US disclosed
EP-1153049-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME Amersham Pharmacia Biotech K.K. (JP) 2001-11-14 EP disclosed
WO-2000044800-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME AMERSHAM PHARMACIA BIOTECH K.K. (JP) 2000-08-03 WO disclosed
EP-0366077-B1 Photopolymerizable resin composition TOKYO OHKA KOGYO CO LTD (JP) 1994-01-26 EP disclosed
US-5236809-A An ethylenically unsaturated compound and a photoinitiator TOKYO OHKA KOGYO CO., LTD. (JP) 1993-08-17 US disclosed
EP-0366077-A2 Photopolymerizable resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 1990-05-02 EP disclosed