SCHEMBL635638

SCHEMBL635638

CC(Cc1ccccc1CC(C)N=C=O)N=C=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.39
GABRB2 P47870 3/20 0.39
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
HTR2A P28223 1/20 0.37
ADRA1A P35348 1/20 0.37
OPRK1 P41145 1/20 0.37
KCNH2 Q12809 1/20 0.37
TSHR P16473 1/20 0.34
HPGD P15428 1/20 0.33
MIF P14174 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
PYCR1 P32322 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2729032 0.82 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C
SCHEMBL21056125 0.82 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C
SCHEMBL27515553 0.82 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C
SCHEMBL17473001 0.81 CYP3A4 (0.39) GABRA1GABRB2NOS3NOS1NOS2
SCHEMBL8763223 0.79 MIF (0.48) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL5710769 0.78 TSHR (0.35) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C
SCHEMBL21753640 0.78 TSHR (0.35) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C
SCHEMBL11785695 0.77 CYP2A6 (0.47) OPRK1TAAR1
SCHEMBL23121590 0.76 PNMT (0.43) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C
SCHEMBL635206 0.76 PNMT (0.43) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107250124-B Novel sulphur compound and the composition for optical material comprising it 三菱瓦斯化学株式会社 2018-07-13 CN disclosed
CN-108264631-A Curing agent and the resin combination for having used the curing agent 协立化学产业株式会社 2018-07-10 CN disclosed
EP-1775315-B1 POLYMERIZABLE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2012-02-22 EP disclosed
US-20080097045-A1 Polymerizable Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-04-24 US disclosed
EP-1775315-A1 POLYMERIZABLE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-04-18 EP disclosed
EP-0349195-B1 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC (US) 1997-05-21 EP disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-5336745-A Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators EXXON CHEMICAL PATENTS INC. (US) 1994-08-09 US disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed