SCHEMBL635206

SCHEMBL635206

CC(Cc1cccc(CC(C)N=C=O)c1)N=C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.43
TAAR1 Q96RJ0 4/20 0.37
SLC6A2 P23975 3/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
MAOA P21397 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
CYP2A6 P11509 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
HTR2A P28223 3/20 0.36
HTR2C P28335 2/20 0.36
HTR2B P41595 2/20 0.36
TSHR P16473 1/20 0.36
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRK1 P41145 1/20 0.35
KCNH2 Q12809 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23121590 1.00 PNMT (0.43) PNMTTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL21056125 0.86 SLC6A2 (0.48) TAAR1SLC6A2SLC6A4SLC6A3MAOA
SCHEMBL2729032 0.86 SLC6A2 (0.48) TAAR1SLC6A2SLC6A4SLC6A3MAOA
SCHEMBL27515553 0.86 SLC6A2 (0.48) TAAR1SLC6A2SLC6A4SLC6A3MAOA
SCHEMBL21753640 0.84 TSHR (0.35) TAAR1SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL5710769 0.84 TSHR (0.35) TAAR1SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL367727 0.83 SLC7A5 (0.38) PNMTNOS3NOS1NOS2
SCHEMBL4090888 0.81 MEN1 (0.37) PNMTTAAR1TSHROPRK1ACHE
SCHEMBL3246197 0.81 TRPA1 (0.43) PNMTTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL8711645 0.77 TACR1 (0.36) PNMTSLC6A2SLC6A3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11926694-B2 Method for producing aqueous carbodiimide-containing liquid NISSHINBO CHEMICAL INC. (JP) 2024-03-12 US claimed
US-20240026064-A1 MODIFIED POLYURETHANE CARRIER SUBSTRATE KUROKI INDUSTRIAL CO., LTD. (TW) 2024-01-25 US claimed
US-11427684-B2 Photopatterned planarization layers for flexible electronics ARES Materials, Inc. (US) 2022-08-30 US claimed
US-20210147631-A1 PHOTOPATTERNED PLANARIZATION LAYERS FOR FLEXIBLE ELECTRONICS ARES Materials, Inc. 2021-05-20 US claimed
WO-2021063760-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-04-08 WO claimed
EP-3757146-A1 METHOD FOR PRODUCING AQUEOUS CARBODIIMIDE-CONTAINING LIQUID Nisshinbo Chemical Inc. (JP) 2020-12-30 EP claimed
US-20200377645-A1 METHOD FOR PRODUCING AQUEOUS CARBODIIMIDE-CONTAINING LIQUID NISSHINBO CHEMICAL INC. (JP) 2020-12-03 US claimed
US-20200255709-A1 OPTICALLY CLEAR ADHESIVES USING SEMI-INTERPENETRATING POLYMER NETWORKS ARES Materials, Inc. 2020-08-13 US claimed
US-20200123410-A1 METHOD FOR FORMING FLEXIBLE COVER LENS FILMS ARES MATERIALS INC. 2020-04-23 US claimed
CN-110317318-A A kind of modified polycarbodiimide curing agent, preparation method and its coating of preparation 立邦工业涂料(上海)有限公司 2019-10-11 CN claimed
EP-1228038-A1 CARBODIIMIDES WITH CARBOXYL OR CARBOXYLATE GROUPS BASF AKTIENGESELLSCHAFT (DE) 2002-08-07 EP claimed
WO-2001034559-A1 CARBODIIMIDES WITH CARBOXYL OR CARBOXYLATE GROUPS BASF AKTIENGESELLSCHAFT (DE) 2001-05-17 WO claimed
EP-0899292-B1 Process for reducing the amine content of recyclate polyols BASF AG (DE) 2001-01-17 EP claimed
US-6130307-A POLY(THIO)URETHANES MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2000-10-10 US claimed
US-5968992-A USING ISOCYANATE CONTAINING ONLY SECONDARY AND/OR TERTIARY, ALIPHATICALLY BOUND ISOCYANATE GROUPS SELECTIVE FOR THE AMINES BASF AKTIENGESELLSCHAFT (DE) 1999-10-19 US claimed
EP-0638066-B1 Process for the preparation of a tertiary-aryl carbotiimide and alternating polycarbodiimide DU PONT (US) 1997-07-02 EP claimed
EP-0638066-A1 CARBODIIMIDES AND PROCESSES THEREFOR. DU PONT (US) 1995-02-15 EP claimed
US-5352400-A Carbodiimides and processes therefor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-04 US claimed
WO-1993022282-A2 CARBODIIMIDES AND PROCESSES THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-11-11 WO claimed
WO-1992007016-A1 POLYHYDROXY URETHANES FORMED BY REACTION OF REDUCED SUGARS AND ORGANIC DIISOCYANATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-30 WO claimed