SCHEMBL21753640

SCHEMBL21753640

C[C@H](Cc1ccc(C[C@@H](C)N=C=O)cc1)N=C=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
CYP3A4 P08684 1/20 0.35
SLC6A2 P23975 3/20 0.35
SLC6A3 Q01959 2/20 0.35
HTR2A P28223 2/20 0.35
SLC6A4 P31645 2/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRK1 P41145 1/20 0.35
KCNH2 Q12809 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
PTGS1 P23219 3/20 0.34
PTGS2 P35354 3/20 0.34
LMNA P02545 2/20 0.34
CYP2C9 P11712 2/20 0.34
AKR1C3 P42330 2/20 0.34
CXCR1 P25024 2/20 0.34
CXCR2 P25025 2/20 0.34
ALB P02768 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5710769 1.00 TSHR (0.35) TSHRCYP3A4SLC6A2SLC6A3HTR2A
SCHEMBL2729032 0.90 SLC6A2 (0.48) TSHRSLC6A2SLC6A3HTR2ASLC6A4
SCHEMBL21056125 0.90 SLC6A2 (0.48) TSHRSLC6A2SLC6A3HTR2ASLC6A4
SCHEMBL27515553 0.90 SLC6A2 (0.48) TSHRSLC6A2SLC6A3HTR2ASLC6A4
SCHEMBL12804676 0.89 CYP3A4 (0.55) TSHRCYP3A4SLC6A2SLC6A3HTR2A
SCHEMBL30081996 0.86 PYCR1 (0.41) TSHRTAAR1
SCHEMBL23121590 0.84 PNMT (0.43) TSHRSLC6A2SLC6A3HTR2ASLC6A4
SCHEMBL635206 0.84 PNMT (0.43) TSHRSLC6A2SLC6A3HTR2ASLC6A4
SCHEMBL19994229 0.83 LDHA (0.39) PTGS2
SCHEMBL8711645 0.79 TACR1 (0.36) TSHRSLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3841137-A1 DRYING AGENT FOR MOISTURE-CURING COMPOSITIONS Covestro Intellectual Property GmbH & Co. KG (DE) 2021-06-30 EP claimed
WO-2020038803-A1 DRYING AGENT FOR MOISTURE-CURING COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2020-02-27 WO claimed