Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357264 | 0.91 | CCR2 (0.65) | CCR2ABCB11 | |
| SCHEMBL6308101 | 0.86 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6598736 | 0.84 | CCR2 (0.73) | CCR2ABCB11 | |
| SCHEMBL6598732 | 0.84 | CCR2 (0.73) | CCR2ABCB11 | |
| SCHEMBL7817668 | 0.82 | CCR2 (0.76) | CCR2ABCB11 | |
| SCHEMBL6596327 | 0.82 | CCR2 (0.76) | CCR2ABCB11 | |
| SCHEMBL6599424 | 0.81 | CCR2 (0.75) | CCR2ABCB11 | |
| SCHEMBL6300905 | 0.81 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6596206 | 0.81 | CCR2 (0.68) | CCR2ABCB11 | |
| SCHEMBL6597662 | 0.80 | CCR2 (0.74) | CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911465-B1 | Anti-inflammatory indole derivatives | ASTRAZENECA AB (SE) | 2005-06-28 | — | — | US | disclosed |
| US-20050026975-A1 | Anti-inflammatory indole derivatives | ASTRAZENECA AB (SE) | 2005-02-03 | — | — | US | disclosed |
| EP-1159269-B1 | ANTI-IMFLAMMATORY INDOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-03-26 | — | — | EP | disclosed |
| EP-1159269-A1 | ANTI-IMFLAMMATORY INDOLE DERIVATIVES | AstraZeneca AB (SE) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000046195-A1 | ANTI-INFLAMMATORY INDOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026975-A1 | Anti-inflammatory indole derivatives | CCR5, CCR2, CCL5 | CCR2 2/4885ABCB11 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.