Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31574686 | 1.00 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL31574679 | 1.00 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL6356494 | 1.00 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL26896762 | 0.87 | MAOA (0.45) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL30907665 | 0.87 | MAOA (0.45) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL26692818 | 0.87 | MAOA (0.45) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL30907668 | 0.87 | MAOA (0.45) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL30658726 | 0.87 | MAOA (0.45) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL6357472 | 0.83 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DMAOA | |
| SCHEMBL31574681 | 0.83 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304533-A1 | THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. | 2025-10-02 | — | — | US | disclosed |
| US-20050239841-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304533-A1 | THERAPEUTIC ALKALOID COMPOUNDS | HTR3B, MTNR1B, PNMT | PDE4B 82/4885PDE4A 99/4885PDE4C 123/4885 |
| US-20050239841-A1 | New compounds | MCHR1, NPY1R, HCRTR1 | PDE4B 815/4885PDE4A 897/4885PDE4C 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.