SCHEMBL63577

SCHEMBL63577

Cc1c(N)cc(O)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.43
CYP3A4 P08684 4/20 0.42
ALDH1A1 P00352 4/20 0.41
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
HPGD P15428 1/20 0.37
KDM4E B2RXH2 3/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
CASP1 P29466 1/20 0.36
PDE10A Q9Y233 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911668 0.86 CA12 (0.46) ACHECYP3A4ALDH1A1ALOX15HSD17B10
SCHEMBL63113 0.80 ACHE (0.65) ACHECYP3A4ALDH1A1ALOX15HSD17B10
SCHEMBL62836 0.79 KDM4E (0.50) ACHECYP3A4ALDH1A1ALOX15HSD17B10
SCHEMBL22187535 0.79 CYP3A4 (0.46) ACHECYP3A4ALDH1A1ALOX15HSD17B10
SCHEMBL29673682 0.79 CYP3A4 (0.46) ACHECYP3A4ALDH1A1ALOX15HSD17B10
SCHEMBL5835200 0.79 ACHE (0.65) ACHECYP3A4ALDH1A1ALOX15HSD17B10
Phloroglucinol SCHEMBL677338 0.77 ACHE (0.61) ACHECYP3A4ALDH1A1ALOX15HSD17B10
SCHEMBL14553798 0.77 CYP3A4 (0.71) CYP3A4ALDH1A1ALOX15TDP1MEN1
SCHEMBL3834395 0.75 ALDH1A1 (0.48) ACHECYP3A4ALDH1A1ALOX15HSD17B10
SCHEMBL16760369 0.75 ACHE (0.40) ACHECYP3A4ALDH1A1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043024-A Solid composition for dyeing keratin 花王株式会社 2024-05-14 CN disclosed
US-10414866-B2 Troger's base polymers having intrinsic microporosity DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-17 US disclosed
WO-2017091357-A1 TROGER'S BASE POLYMERS HAVING INTRINSIC MICROPOROSITY DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-01 WO disclosed
EP-2330159-B1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS CO LTD (JP) 2013-04-24 EP disclosed
US-8129869-B2 Electret and electrostatic induction conversion device ASAHI GLASS COMPANY, LIMITED (JP) 2012-03-06 US disclosed
US-20110166299-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS COMPANY, LIMITED 2011-07-07 US disclosed
EP-2330159-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE Asahi Glass Company Limited (JP) 2011-06-08 EP disclosed