Butyramide

Butyramide

SCHEMBL6357880

C=C(C)C(=O)NCCC.CCCC(N)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.38
TDP1 Q9NUW8 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
EPHX1 P07099 1/20 0.33
PAOX Q6QHF9 1/20 0.32
CASP2 P42575 1/20 0.32
MCL1 Q07820 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PLA2G2A P14555 2/20 0.32
MEN1 O00255 1/20 0.32
FAAH O00519 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionamide SCHEMBL6358221 0.89 TDP1 (0.37) CTSDTDP1MMP1MMP2MMP3
Acetamide SCHEMBL6354454 0.88 TDP1 (0.40) CTSDTDP1MMP1MMP2MMP3
SCHEMBL733023 0.86 TDP1 (0.50) CTSDTDP1MMP1MMP2MMP3
Methylamine SCHEMBL2363145 0.86 MMP1 (0.40) CTSDTDP1MMP1MMP2MMP3
SCHEMBL149370 0.86
Guanidine SCHEMBL28149619 0.85 TDP1 (0.37) CTSDTDP1MMP1MMP2MMP3
SCHEMBL6402194 0.84 TDP1 (0.40) TDP1PLA2G2ATGFBR1
Methylamine SCHEMBL6561969 0.84 MMP1 (0.39) CTSDTDP1MMP1MMP2MMP3
Hydrochloric Acid SCHEMBL3148805 0.84 MMP1 (0.41) MMP1MMP2MMP3MMP9EPHX1
Ammonia Solution, Strong SCHEMBL27993992 0.84 MMP1 (0.41) MMP1MMP2MMP3MMP9EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1591462-A2 Temperature-responsive polymer compound and process for producing the same Amersham Biosciences KK (JP) 2005-11-02 EP disclosed
US-6956077-B1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK (JP) 2005-10-18 US disclosed
US-20050224415-A1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK 2005-10-13 US disclosed
EP-1153049-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME Amersham Pharmacia Biotech K.K. (JP) 2001-11-14 EP disclosed
WO-2000044800-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME AMERSHAM PHARMACIA BIOTECH K.K. (JP) 2000-08-03 WO disclosed