SCHEMBL6402194

SCHEMBL6402194

C=C(C)C(=O)NCCC(N)=O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
TGFBR1 P36897 1/20 0.34
ECE1 P42892 1/20 0.33
PLA2G2A P14555 1/20 0.32
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7113895 0.89 TDP1 (0.39) TDP1TGFBR1PLA2G2AKDM4EMAPK1
Butyramide SCHEMBL6357880 0.84 CTSD (0.38) TDP1TGFBR1PLA2G2A
SCHEMBL15535068 0.82 ALDH1A1 (0.41) TDP1TGFBR1PLA2G2AALDH1A1KDM4E
SCHEMBL316224 0.81 TGFBR1 (0.41) TDP1TGFBR1ALDH1A1KDM4EMAPK1
Urea SCHEMBL28349229 0.80 TDP1 (0.34) TDP1TGFBR1PLA2G2A
SCHEMBL472252 0.80 TDP1 (0.42) TDP1TGFBR1ALDH1A1KDM4EMAPK1
SCHEMBL907324 0.80 PLA2G2A (0.48) TGFBR1ECE1PLA2G2AALDH1A1KDM4E
SCHEMBL13205118 0.80 PLA2G2A (0.36) TDP1TGFBR1PLA2G2AALDH1A1KDM4E
Propionamide SCHEMBL6358221 0.79 TDP1 (0.37) TDP1TGFBR1ALDH1A1KDM4E
SCHEMBL9226642 0.79 TDP1 (0.33) TDP1TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230294380-A1 Multi-Layer Film, and Multi-Layer Structure In Which Same Is Used KURARAY CO., LTD. (JP) 2023-09-21 US disclosed
EP-4173822-A1 MULTI-LAYER FILM, AND MULTI-LAYER STRUCTURE IN WHICH SAME IS USED Kuraray Co., Ltd. (JP) 2023-05-03 EP disclosed
EP-2979686-A1 ARTIFICIAL NAIL COMPOSITION, ARTIFICIAL NAIL, METHOD FOR FORMING ARTIFICIAL NAIL, METHOD FOR REMOVING ARTIFICIAL NAIL, AND NAIL ART KIT FUJIFILM Corporation (JP) 2016-02-03 EP disclosed
US-20150342320-A1 ARTIFICIAL NAIL COMPOSITION, ARTIFICIAL NAIL, METHOD FOR FORMING ARTIFICIAL NAIL, METHOD FOR REMOVING ARTIFICIAL NAIL, AND NAIL ART KIT FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150342320-A1 ARTIFICIAL NAIL COMPOSITION, ARTIFICIAL NAIL, METHOD FOR FORMING ARTIFICIAL NAIL, METHOD FOR REMOVING ARTIFICIAL NAIL, AND NAIL ART KIT FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20050075416-A1 Process for preparing microencapsulated pigment, microencapsulated pigment, aqueous dispersion, and ink for ink jet recording SEIKO EPSON CORPORATION 2005-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150342320-A1 ARTIFICIAL NAIL COMPOSITION, ARTIFICIAL NAIL, METHOD FOR FORMING ARTIFICIAL NAIL, METHOD FOR REMOVING ARTIFICIAL NAIL, AND NAIL ART KIT POLR1C, PIK3C3, PRKDC TDP1 2314/4885TGFBR1 3614/4885ECE1 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.