Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.62 |
| ▸ | CA2 | P00918 | 10/20 | 0.62 |
| ▸ | CA9 | Q16790 | 6/20 | 0.62 |
| ▸ | CA12 | O43570 | 5/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 2/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Disulfone SCHEMBL493732 | 0.82 | HTR6 (0.65) | CA1CA2CA9CA12CA7 | |
| Disulfone SCHEMBL8427811 | 0.82 | HTR6 (0.65) | CA1CA2CA9CA12CA7 | |
| Benzenesulfonamide SCHEMBL29825137 | 0.77 | CA2 (1.00) | CA1CA2CA9CA12CA7 | |
| Benzenesulfonamide SCHEMBL1332409 | 0.77 | CA2 (1.00) | CA1CA2CA9CA12CA7 | |
| Benzenesulfonamide SCHEMBL6868390 | 0.77 | CA2 (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL19479299 | 0.77 | CA2 (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL13835654 | 0.77 | HTR6 (0.58) | CA1CA2CA9CA12CA7 | |
| Benzenesulfonamide SCHEMBL729 | 0.77 | CA2 (1.00) | CA1CA2CA9CA12CA7 | |
| Benzenesulfonamide SCHEMBL7517039 | 0.74 | CA2 (0.94) | CA1CA2CA9CA12CA7 | |
| Benzenesulfonamide SCHEMBL3100364 | 0.74 | CA2 (0.94) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070709-A2 | 3-OXY-7-SULFAMYL-3,4-DIHYDRO-1,2,4-BENZOTHIADAZINE-1,1-DIOXIDE DERIVATIVES HAVING DIURETIC AND/OR NATRIURETIC ACTIVITY | FARMA INVENT B.V. (NL) | 2001-09-27 | — | — | WO | claimed |
| CN-111747897-A | Hexaarylbisimidazole photoinitiator and application thereof | 常州格林感光新材料有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-100406441-C | Cyclic amine compounds | KOWA CO (JP) | 2008-07-30 | — | — | CN | disclosed |
| US-6960688-B2 | Use of compounds for the elevation of pyruvate dehydrogenase activity | ASTRAZENECA AB (SE) | 2005-11-01 | — | — | US | disclosed |
| CN-1604893-A | Cyclic amine compound | KOWA CO (JP) | 2005-04-06 | — | — | CN | disclosed |
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |