⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105038 | 0.91 | — | — | |
| SCHEMBL8773839 | 0.80 | ACHE (0.33) | — | |
| SCHEMBL17286403 | 0.74 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL63721 | 0.71 | GPR3 (0.43) | — | |
| SCHEMBL11485064 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL8773840 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL28431559 | 0.65 | TSHR (0.50) | — | |
| 1,2-Dichlorobenzene SCHEMBL21634789 | 0.63 | TSHR (0.71) | — | |
| 1,2-Dichlorobenzene SCHEMBL31146806 | 0.63 | TSHR (0.71) | — | |
| SCHEMBL1683235 | 0.63 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245089-A1 | PROCESSES FOR PREPARING TETRALIN COMPOUNDS | ARCUS BIOSCIENCES, INC. (US) | 2025-11-27 | — | — | WO | claimed |
| US-20250353815-A1 | AMINO ACID HAVING FLUORINE AT a-POSITION, AND DERIVATIVE OF SAME | SYNCREST INC. (JP) | 2025-11-20 | — | — | US | claimed |
| EP-4520750-A1 | AMINO ACID HAVING FLUORINE AT ALPHA-POSITION, AND DERIVATIVE OF SAME | SynCrest Inc. (JP) | 2025-03-12 | — | — | EP | claimed |
| US-12145901-B1 | Process for preparing tetralin compounds | ARCUS BIOSCIENCES, INC. (US) | 2024-11-19 | — | — | US | claimed |
| US-11873289-B2 | Pyrazole compounds and preparation thereof | MyoKardia, Inc. (US) | 2024-01-16 | — | — | US | claimed |
| EP-4299412-A1 | METHOD FOR CONTROLLING A POWER CONSUMPTION OF A FLEET OF RAIL VEHICLES | Siemens Mobility GmbH (DE) | 2024-01-03 | — | — | EP | claimed |
| WO-2023243699-A1 | AMINO ACID HAVING FLUORINE AT α-POSITION, AND DERIVATIVE OF SAME | シンクレスト株式会社 | 2023-12-21 | — | — | WO | claimed |
| CN-117202096-A | Ship personnel positioning system | 中国舰船研究设计中心 | 2023-12-08 | — | — | CN | claimed |
| CN-116782129-A | WiFi fingerprint positioning method for personnel position in ship | 中国舰船研究设计中心 | 2023-09-19 | — | — | CN | claimed |
| US-20230101833-A1 | CHEMICAL TREATMENT FOR PREPARING METAL ELECTRODES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2023-03-30 | — | — | US | claimed |
| US-20210053940-A1 | PYRAZOLE COMPOUNDS AND PREPARATION THEREOF | SRF LIMITED (IN) | 2021-02-25 | — | — | US | claimed |
| EP-3746434-A1 | PYRAZOLE COMPOUNDS AND PREPARATION THEREOF | MyoKardia, Inc. (US) | 2020-12-09 | — | — | EP | claimed |
| WO-2020201975-A2 | NOVEL PROCESS FOR THE PREPARATION OF FILGOTINIB AND INTERMEDIATES THEREOF | UNICHEM LABORATORIES LIMITED (IN) | 2020-10-08 | — | — | WO | claimed |
| CN-111670184-A | Pyrazole compounds and process for preparing the same | 迈奥卡迪亚公司 | 2020-09-15 | — | — | CN | claimed |
| WO-2019150392-A1 | PYRAZOLE COMPOUNDS AND PREPARATION THEREOF | SRF LIMITED (IN) | 2019-08-08 | — | — | WO | claimed |
| US-9024093-B2 | Fluorination of organic compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-05-05 | — | — | US | claimed |
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | claimed |
| WO-2009100014-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-08-13 | — | — | WO | claimed |
| US-6365246-B1 | SOLUTION OR SLURRY SOLVENT ABSORBS HEAT OF VAPORIZATION FOR STABILITY OF QUATERNARY NITROGEN COMPOUNDS SUCH AS 1-CHLOROMETHYL-4-FLUORO-1,4-DIAZONIABICYCLO(2.2.2)OCTANE BIS(TETRAFLUOROBORATE) | AIR PRODUCTS AND CHEMICALS, INC. | 2002-04-02 | — | — | US | claimed |
| EP-0992494-A1 | Package for safe storage of electrophilic fluorinating agent | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-04-12 | — | — | EP | claimed |