SCHEMBL6358305

SCHEMBL6358305

C=CC(=O)Nc1ccc(NC(C)=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 10/20 0.71
▸ F13A1 P00488 1/20 0.66
▸ LMNA P02545 1/20 0.66
▸ TGM1 P22735 1/20 0.66
▸ TGM3 Q08188 1/20 0.66
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ HTT P42858 1/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ KMT2A Q03164 4/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ MAPT P10636 2/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ CA12 O43570 1/20 0.57
▸ BRD4 O60885 1/20 0.57
▸ NR1I2 O75469 1/20 0.57
▸ CA1 P00915 1/20 0.57
▸ CA2 P00918 1/20 0.57
▸ MB P02144 1/20 0.57
▸ CYP1A1 P04798 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22820605 0.89 TGM2 (0.59) TGM2F13A1LMNATGM1TGM3
SCHEMBL439369 0.89 TGM2 (0.79) TGM2F13A1LMNATGM1TGM3
SCHEMBL6355891 0.85 TGM2 (0.65) TGM2SMN1; SMN2L3MBTL1KMT2AMEN1
SCHEMBL7470743 0.84 TGM2 (0.67) TGM2F13A1LMNATGM1TGM3
SCHEMBL648950 0.83 TGM2 (1.00) TGM2F13A1LMNATGM1TGM3
SCHEMBL15693010 0.83 TGM2 (0.71) TGM2F13A1LMNATGM1TGM3
SCHEMBL21787312 0.82 TGM2 (0.65) TGM2F13A1LMNATGM1TGM3
SCHEMBL861674 0.82 SMN1; SMN2 (0.84) SMN1; SMN2HTTL3MBTL1KMT2AMEN1
Acetic Acid SCHEMBL11194307 0.81 TGM2 (0.62) TGM2F13A1LMNATGM1TGM3
SCHEMBL7270679 0.81 TGM2 (0.68) TGM2F13A1LMNATGM1TGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304166-B2 Heat sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-11-06 — — US disclosed
US-8304166-B2 Heat sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-11-06 — — US disclosed
US-20100055610-A1 HEAT SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-03-04 — — US disclosed
US-20100055610-A1 HEAT SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-03-04 — — US disclosed
EP-2159049-A1 A heat-sensitive positive-working lithographic printing plate precursor Agfa Graphics N.V. (BE) 2010-03-03 — — EP disclosed
EP-1591462-A2 Temperature-responsive polymer compound and process for producing the same Amersham Biosciences KK (JP) 2005-11-02 — — EP disclosed
US-6956077-B1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK (JP) 2005-10-18 — — US disclosed
US-20050224415-A1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK 2005-10-13 — — US disclosed
EP-1153049-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME Amersham Pharmacia Biotech K.K. (JP) 2001-11-14 — — EP disclosed
WO-2000044800-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME AMERSHAM PHARMACIA BIOTECH K.K. (JP) 2000-08-03 — — WO disclosed
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