SCHEMBL7270679

SCHEMBL7270679

[CH2]c1ccc(NC(=O)C=C)cc1

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 14/20 0.68
F13A1 P00488 4/20 0.68
TGM1 P22735 4/20 0.68
LMNA P02545 1/20 0.68
TGM3 Q08188 1/20 0.68
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
TDP2 O95551 1/20 0.43
GSTO1 P78417 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439369 0.91 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL133445 0.83 TGM2 (0.68) TGM2F13A1TGM1LMNATGM3
SCHEMBL28703875 0.83 TGM2 (0.68) TGM2F13A1TGM1LMNATGM3
SCHEMBL3064236 0.81 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL6481884 0.81 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL7785803 0.81 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL6358305 0.81 TGM2 (0.71) TGM2F13A1TGM1LMNATGM3
SCHEMBL10986032 0.81 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL1381911 0.81 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL19393388 0.81 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140371459-A1 INDUSTRIAL PROCESS FOR PREPARATION OF 1,2-DIHYDROQUINOLINE DERIVATIVE OR A SALT THEREOF, AND INTERMEDIATE FOR PREPARATION THEREOF SANTEN PHARMACEUTICAL CO., LTD. (JP) 2014-12-18 US disclosed
EP-2805948-A1 INDUSTRIAL PROCESS FOR PREPARATION OF 1,2-DIHYDROQUINOLINE DERIVATIVE OR A SALT THEREOF, AND INTERMEDIATE FOR PREPARATION THEREOF Santen Pharmaceutical Co., Ltd (JP) 2014-11-26 EP disclosed
US-6660484-B2 Colorimetric glycopolythiophene biosensors REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-12-09 US disclosed
US-20010026915-A1 Colorimetric glycopolythiophene biosensors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140371459-A1 INDUSTRIAL PROCESS FOR PREPARATION OF 1,2-DIHYDROQUINOLINE DERIVATIVE OR A SALT THEREOF, AND INTERMEDIATE FOR PREPARATION THEREOF NR3C2, NR5A1, NR3C1 TGM2 3844/4885F13A1 4136/4885TGM1 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.