SCHEMBL6355891

SCHEMBL6355891

C=CC(=O)Nc1cccc(NC(C)=O)c1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 3/20 0.65
ALDH1A1 P00352 3/20 0.58
HSD17B10 Q99714 2/20 0.58
CYP1A2 P05177 1/20 0.58
RAB9A P51151 2/20 0.57
POLB P06746 1/20 0.57
NR4A1 P22736 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
TP53 P04637 1/20 0.53
NAPRT Q6XQN6 1/20 0.52
LPAR1 Q92633 1/20 0.51
LPAR2 Q9HBW0 1/20 0.51
MAPT P10636 1/20 0.51
EGFR P00533 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4103284 0.91 TGM2 (0.76) TGM2LPAR1LPAR2EGFR
SCHEMBL22600367 0.86 TGM2 (0.65) TGM2LPAR1LPAR2EGFR
SCHEMBL6358305 0.85 TGM2 (0.71) TGM2ALDH1A1HSD17B10RAB9APOLB
SCHEMBL21469043 0.85 TGM2 (0.59) TGM2LPAR1LPAR2EGFR
SCHEMBL1901172 0.84 ALDH1A1 (0.76) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL1925142 0.84 KMT2A (0.71) TGM2ALDH1A1CYP1A2RAB9APOLB
SCHEMBL20750046 0.83 TGM2 (0.58) TGM2LPAR1LPAR2EGFRMEN1
SCHEMBL9312293 0.82 MEN1 (0.73) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL31536255 0.82 TGM2 (0.65) TGM2HSD17B10EGFRMEN1KMT2A
SCHEMBL1383747 0.82 TGM2 (0.65) TGM2HSD17B10EGFRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9690195-B2 Lithographic printing plate precursors and processes for preparing lithographic printing plates FUJIFILM CORPORATION (JP) 2017-06-27 US disclosed
EP-1591462-A2 Temperature-responsive polymer compound and process for producing the same Amersham Biosciences KK (JP) 2005-11-02 EP disclosed
US-6956077-B1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK (JP) 2005-10-18 US disclosed
US-20050224415-A1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK 2005-10-13 US disclosed
EP-1153049-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME Amersham Pharmacia Biotech K.K. (JP) 2001-11-14 EP disclosed
WO-2000044800-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME AMERSHAM PHARMACIA BIOTECH K.K. (JP) 2000-08-03 WO disclosed