Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.72 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.72 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209179 | 0.90 | AKR1C2 (0.56) | AKR1C2AKR1C1AKR1C4AKR1C3MAOB | |
| SCHEMBL6352019 | 0.90 | AKR1C2 (0.78) | AKR1C2AKR1C1SMPD1AKR1C4AKR1C3 | |
| SCHEMBL6357045 | 0.87 | AKR1C2 (0.74) | AKR1C2AKR1C1SMPD1AKR1C4AKR1C3 | |
| SCHEMBL6353185 | 0.86 | AKR1C2 (0.72) | AKR1C2AKR1C1SMPD1AKR1C4AKR1C3 | |
| SCHEMBL6360447 | 0.84 | AKR1C2 (0.82) | AKR1C2AKR1C1AKR1C4AKR1C3NR1H4 | |
| SCHEMBL6350825 | 0.84 | AKR1C2 (1.00) | AKR1C2AKR1C1AKR1C4AKR1C3NR1H4 | |
| SCHEMBL6359823 | 0.83 | AKR1C2 (0.78) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6352870 | 0.83 | AKR1C2 (0.70) | AKR1C2AKR1C1SMPD1AKR1C4AKR1C3 | |
| SCHEMBL6352473 | 0.83 | AKR1C2 (0.77) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6350824 | 0.82 | KCNK2 (0.62) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885SMPD1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.