Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271629 | 0.81 | PDPK1 (0.40) | CSNK2A1CSNK2A2CSNK2BMAPTKDM4E | |
| SCHEMBL6356987 | 0.75 | PNP (0.54) | DPP4HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL3158628 | 0.75 | DPP4 (0.50) | DPP4TRAP1HSP90B1HSP90AA1 | |
| SCHEMBL6358281 | 0.72 | NUDT1 (0.58) | DPP4TRAP1HSP90B1CSNK2A1HSP90AA1 | |
| SCHEMBL1270584 | 0.71 | PNP (0.66) | HSD17B10MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6358728 | 0.71 | MAPT (0.39) | HSD17B10HTTTRAP1HSP90B1CSNK2A1 | |
| SCHEMBL8080150 | 0.69 | DPP4 (0.44) | DPP4L3MBTL1 | |
| SCHEMBL3651176 | 0.69 | HSD17B10 (0.39) | HSD17B10HTTCSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL6363421 | 0.68 | DPP4 (0.43) | DPP4TRAP1HSP90B1ALDH1A1CYP1A2 | |
| SCHEMBL23851630 | 0.65 | KDM4E (0.36) | DPP4HSD17B10TRAP1HSP90B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1923171-B | Compound recipe anti-cancer drugs slow release agent comprising anticancer antibiotics and synergist thereof | JINAN KANGQUAN PHARMACEUTICAL CO LTD | 2010-05-19 | — | — | CN | disclosed |
| CN-100563710-C | The anticancer medicine slow-release preparation containing that contains pyrimidine analogue | JINAN SHUAIHUA MEDICINE SCI TE (CN) | 2009-12-02 | — | — | CN | disclosed |
| CN-100500215-C | Sustained-release injection containing methotrexate and synergist thereof | JINAN SHUAIHUA MEDICINE SCI TE (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-101380306-A | Compound platinum medicine sustained-release agent | JINAN SHUAIHUA PHARMACEUTICAL (CN) | 2009-03-11 | — | — | CN | disclosed |
| CN-101380297-A | Compound platinum medicine sustained-release agent | JINAN SHUAIHUA PHARMACEUTICAL (CN) | 2009-03-11 | — | — | CN | disclosed |
| CN-101292956-A | Sustained-release injection containing methotrexate and its synergistic agent | JINAN SHUAIHUA PHARMACEUTICAL (CN) | 2008-10-29 | — | — | CN | disclosed |
| CN-101292955-A | Sustained-release injection containing fluorouracil synergistic agent and preparation method thereof | JINAN SHUAIHUA PHARMACEUTICAL (CN) | 2008-10-29 | — | — | CN | disclosed |
| CN-101244034-A | Sustained-release agent containing taxone and its synergistic agent | JINAN KANGQUAN PHARMACEUTICAL (CN) | 2008-08-20 | — | — | CN | disclosed |
| CN-101244033-A | Sustained-release agent containing taxone and its synergistic agent | JINAN KANGQUAN PHARMACEUTICAL (CN) | 2008-08-20 | — | — | CN | disclosed |
| CN-100386115-C | Anti-cancer medicine composition | QINGZHONG KONG (CN) | 2008-05-07 | — | — | CN | disclosed |
| EP-0775142-B1 | SUBSTITUTED O6 -BENZYLGUANINES | US HEALTH (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6303604-B1 | USED AS ANTINEOPLASTIC ALKYLATING AGENT WHICH CAUSES CYTOTOXIC LESIONS AT THE O.SUP.6-POSITION OF QUANINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-10-16 | — | — | US | disclosed |
| EP-1142893-A1 | Substituted O6-benzylguanines and 6(4)-benzyloxypyrimidines | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6172070-B1 | IN POLYOXYETHYLENE GLYCOL CARRIER | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-01-09 | — | — | US | disclosed |
| US-5958932-A | ANTITUMOR AGENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-09-28 | — | — | US | disclosed |
| US-5916894-A | Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-06-29 | — | — | US | disclosed |
| US-5753668-A | Substituted benzyloxypyrimidines and their inactivation of O6 -alkylguanine-DNA alkyltransferase | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0775142-A1 | SUBSTITUTED O6 -BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5525606-A | CHEMOTHERAPEUTIC ANTITUMOR AGENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1996004281-A1 | SUBSTITUTED O6-BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-02-15 | — | — | WO | disclosed |