Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562509 | 1.00 | TOP1 (0.48) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL28238771 | 0.98 | TOP1 (0.52) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL27442584 | 0.80 | FAAH (0.48) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL11781984 | 0.78 | EP300 (0.44) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL28474044 | 0.78 | FAAH (0.52) | MAPTFABP4BLMHSD17B10USP2 | |
| SCHEMBL28485780 | 0.78 | FAAH (0.52) | MAPTFABP4BLMHSD17B10USP2 | |
| SCHEMBL27674717 | 0.77 | EPHX2 (0.38) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL27410583 | 0.77 | ALDH1A1 (0.39) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL5136587 | 0.77 | TERT (0.50) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL20996668 | 0.76 | TSHR (0.42) | TOP1PPARGPPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198472-A1 | AMINE-MODIFIED PSEUDOMYCIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2001005816-A1 | AMINE-MODIFIED PSEUDOMYCIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-01-25 | — | — | WO | claimed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20050136180-A1 | Method of coating a substrate with a fluoropolymer | 3M INNOVATIVE PROPERTIES COMPANY | 2005-06-23 | — | — | US | disclosed |
| EP-1198472-A1 | AMINE-MODIFIED PSEUDOMYCIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001005816-A1 | AMINE-MODIFIED PSEUDOMYCIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |