SCHEMBL6358956

SCHEMBL6358956

Cl[Zr](Cl)C(Cc1cccc2c1-c1ccccc1C2)c1cccc2c1-c1ccccc1C2

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
PNMT P11086 1/20 0.36
POLB P06746 1/20 0.33
HTR2B P41595 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5348067 0.79 PNMT (0.51) DRD2DRD4DRD3PNMTHTR2B
SCHEMBL6347029 0.75 MAP3K9 (0.32) PNMT
SCHEMBL7189694 0.74 DRD3 (0.51) DRD2DRD4DRD3PNMTPOLB
SCHEMBL9762612 0.73 DRD2 (0.48) DRD2DRD4DRD3PNMTPOLB
SCHEMBL7184376 0.72 DRD2 (0.50) DRD2DRD4DRD3PNMTPOLB
SCHEMBL8160473 0.70 MAOA (0.42) DRD2DRD4DRD3POLBHTR2B
SCHEMBL22310126 0.70 HTR2B (0.43) DRD2DRD4DRD3PNMTPOLB
SCHEMBL21694426 0.70 DRD2 (0.48) DRD2DRD4DRD3PNMTPOLB
SCHEMBL16792809 0.70 PNMT (0.62) DRD2DRD4DRD3PNMTPOLB
SCHEMBL5540652 0.70 DRD3 (0.48) DRD2DRD4DRD3PNMTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6844398-B2 Ethylenic copolymer, composition containing said copolymer, and ethylenic copolymer film IDEMITSU KOSAN CO., LTD. (JP) 2005-01-18 US disclosed
US-20020188087-A1 Ethylenic copolymer, composition containing said copolymer, and ethylenic copolymer film IDEMITSU KOSAN CO., LTD. (JP) 2002-12-12 US disclosed
US-6441116-B1 FILM FORMED FROM AN ETHYLENIC COPOLYMER WHICH HAS A NARROW MOLECULAR WEIGHT DISTRIBUTION AND A NARROW BRANCHING DEGREE DISTRIBUTION AND HAS A CONTROLLED COMPOSITIONAL DISTRIBUTION PROFILE, TEAR STRENGTH, HEAT SEALING IDEMITSU KOSAN CO., LTD. (JP) 2002-08-27 US disclosed