Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.73 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.73 |
| ▸ | RELA | Q04206 | 1/20 | 0.73 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353666 | 0.88 | AKR1C2 (0.73) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6352473 | 0.88 | AKR1C2 (0.77) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6353698 | 0.88 | KCNK2 (0.57) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6346661 | 0.85 | AKR1C2 (0.73) | AKR1C2AKR1C1NPC1RAB9AAKR1C4 | |
| SCHEMBL6350825 | 0.85 | AKR1C2 (1.00) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6353697 | 0.84 | AKR1C2 (0.64) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6355650 | 0.83 | AKR1C2 (0.84) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6360447 | 0.83 | AKR1C2 (0.82) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14075205 | 0.83 | AKR1C2 (0.90) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6359823 | 0.82 | AKR1C2 (0.78) | AKR1C2AKR1C1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885NPC1 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.