Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161762 | 0.89 | S1PR4 (0.44) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL6361283 | 0.83 | S1PR4 (0.40) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL3168592 | 0.82 | S1PR4 (0.51) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL27625069 | 0.82 | S1PR4 (0.48) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL3211767 | 0.81 | MAPT (0.35) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL28696650 | 0.78 | S1PR4 (0.47) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL4404101 | 0.76 | S1PR4 (0.42) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL4406257 | 0.76 | S1PR4 (0.42) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL6157675 | 0.76 | DHFR (0.42) | S1PR4MAPTHPGDNPC1RAB9A | |
| SCHEMBL6566114 | 0.75 | S1PR4 (0.41) | S1PR4MAPTLMNAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182025-A1 | Amidinylphenyl compounds and their use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182025-A1 | Amidinylphenyl compounds and their use as fungicides | OR10J3, CBR3, C3AR1 | S1PR4 1585/4885MAPT 4646/4885LMNA 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.