Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705870 | 0.81 | DHFR (0.40) | DHFRMAOACD44GAAMAPT | |
| SCHEMBL6156538 | 0.81 | GAA (0.37) | DHFRMAOAGAAMAPTL3MBTL1 | |
| SCHEMBL11794328 | 0.79 | CD44 (0.39) | DHFRMAOACD44GAAMAPT | |
| SCHEMBL18835661 | 0.76 | KDM4E (0.46) | CD44GAAMAPTL3MBTL1MEN1 | |
| SCHEMBL14291307 | 0.76 | KDM4E (0.45) | MAOAMAPTALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL6359199 | 0.76 | S1PR4 (0.45) | GAAMAPTKMT2AALDH1A1NPSR1 | |
| SCHEMBL6157021 | 0.75 | DHFR (0.32) | DHFRMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3341078 | 0.74 | MAOA (0.43) | DHFRMAOACD44GAAMAPT | |
| SCHEMBL12901934 | 0.73 | CSNK2A1 (0.50) | DHFRMAOACD44GAAMAPT | |
| SCHEMBL6358274 | 0.73 | LMNA (0.32) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182025-A1 | Amidinylphenyl compounds and their use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-08-18 | — | — | US | disclosed |
| EP-1501789-A1 | AMIDINYLPHENYL COMPOUNDS AND THEIR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093224-A1 | AMIDINYLPHENYL COMPOUNDS AND THEIR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182025-A1 | Amidinylphenyl compounds and their use as fungicides | OR10J3, CBR3, C3AR1 | DHFR 1514/4885MAOA 1239/4885CD44 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.