Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368411 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL2368417 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL2368544 | 0.85 | KCNA5 (0.44) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL3415627 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL3415634 | 0.83 | KDM4E (0.39) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL2369196 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL2369234 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL2368976 | 0.80 | KCNH2 (0.48) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL2369248 | 0.79 | KCNA5 (0.45) | SMN1; SMN2KCNA5KMT2AMEN1PRKCI | |
| SCHEMBL3384941 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2KMT2AMEN1PRKCIALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | SMN1; SMN2 1520/4885KCNA5 8/4885KMT2A 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.