Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866699 | 0.89 | PTGER4 (0.44) | PTGER4PTGER3PTGER2P2RX7KMT2A | |
| SCHEMBL2034493 | 0.86 | PTGER4 (0.36) | PTGER4PTGER3PTGER2P2RX7KMT2A | |
| SCHEMBL11364946 | 0.85 | PTGER4 (0.48) | PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL13651410 | 0.83 | PER2 (0.42) | P2RX7KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL2782894 | 0.83 | PER2 (0.42) | P2RX7KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL12993185 | 0.83 | PTGER4 (0.52) | PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL12298852 | 0.83 | PTGER4 (0.52) | PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL280622 | 0.82 | PTGER4 (0.34) | PTGER4PTGER3PTGER2P2RX7KMT2A | |
| SCHEMBL265281 | 0.80 | PTGER3 (0.50) | PTGER4PTGER3PTGER2P2RX7KMT2A | |
| SCHEMBL11949258 | 0.80 | L3MBTL1 (0.39) | P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129819-A1 | GEL COMPOSITIONS FOR ADMINISTRATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS | MEDORTUS (UK) LTD (GB) | 2012-05-24 | — | — | US | disclosed |
| EP-2419138-A1 | GEL COMPOSITIONS FOR ADMINISTRATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS | Medortus (UK) Ltd (GB) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010118461-A1 | GEL COMPOSITIONS FOR ADMINISTRATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS | VANCAILLIE THIERRY (AU) | 2010-10-21 | — | — | WO | disclosed |