Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 14/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782894 | 1.00 | PER2 (0.42) | PER2P2RX7KMT2ACHRM2CHRM4 | |
| SCHEMBL10491078 | 0.88 | P2RX7 (0.37) | PER2P2RX7KMT2ACHRM2CHRM4 | |
| SCHEMBL635958 | 0.83 | PTGER4 (0.40) | P2RX7KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL11929360 | 0.83 | L3MBTL1 (0.39) | P2RX7KMT2A | |
| SCHEMBL11949258 | 0.83 | L3MBTL1 (0.39) | P2RX7KMT2A | |
| SCHEMBL12301049 | 0.83 | L3MBTL1 (0.39) | P2RX7KMT2A | |
| SCHEMBL2037183 | 0.83 | P2RX7 (0.39) | PER2P2RX7 | |
| SCHEMBL14839577 | 0.83 | PTGER4 (0.40) | PER2P2RX7KMT2ACHRM2CHRM4 | |
| SCHEMBL11518007 | 0.83 | KMT2A (0.38) | P2RX7KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL2034493 | 0.82 | PTGER4 (0.36) | PER2P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608637-B2 | Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-27 | — | — | US | disclosed |