Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 7/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359651 | 1.00 | ALDH1A1 (0.56) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL22687091 | 0.88 | CTSL (0.57) | CTSLSYKPPARAKMT2AL3MBTL1 | |
| SCHEMBL22687090 | 0.88 | CTSL (0.57) | CTSLSYKPPARAKMT2AL3MBTL1 | |
| SCHEMBL6153463 | 0.86 | ALDH1A1 (0.69) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL3944460 | 0.86 | ALDH1A1 (0.69) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL3944464 | 0.86 | ALDH1A1 (0.69) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL6360121 | 0.86 | CTSL (0.45) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL6360124 | 0.86 | CTSL (0.45) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL6360125 | 0.86 | CTSL (0.45) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL8234039 | 0.84 | CTSL (0.59) | ALDH1A1GAACTSLSYKEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100334-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050234065-A1 | Dipeptidyl peptidase-IV inhibitors | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234065-A1 | Dipeptidyl peptidase-IV inhibitors | ALPI, DPP4, SI | ALDH1A1 247/4885GAA 373/4885TSHR 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.