Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 2/20 | 0.57 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 2/20 | 0.55 |
| ▸ | PLK1 | P53350 | 3/20 | 0.55 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353430 | 0.91 | MAPT (0.57) | MAPTMEN1KMT2AKCNK2CA2 | |
| SCHEMBL6359401 | 0.88 | ALB (0.63) | MAPTMEN1KMT2APKMALB | |
| SCHEMBL6359036 | 0.88 | MEN1 (0.66) | MAPTMEN1KMT2AALBPLK1 | |
| SCHEMBL6357140 | 0.88 | MEN1 (0.60) | MAPTMEN1KMT2ACA2ALDH1A1 | |
| SCHEMBL6349721 | 0.88 | MEN1 (0.57) | MAPTMEN1KMT2ACA2KDM4E | |
| SCHEMBL7244828 | 0.87 | F10 (0.71) | MAPTMEN1KMT2ANPSR1F10 | |
| SCHEMBL6350083 | 0.86 | SERPINE1 (0.68) | MAPTMEN1KMT2AALBNPC1 | |
| SCHEMBL6355568 | 0.86 | PLK1 (0.63) | MAPTMEN1KMT2AALBPLK1 | |
| SCHEMBL6346687 | 0.85 | ALB (0.60) | MAPTMEN1KMT2APKMF10 | |
| SCHEMBL6349877 | 0.85 | CHEK1 (0.66) | MAPTMEN1KMT2APKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MAPT 4753/4885MEN1 3274/4885KMT2A 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.