Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148031 | 1.00 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL6238941 | 0.87 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL6238936 | 0.87 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL5148637 | 0.83 | CA1 (0.39) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL9079524 | 0.83 | CA1 (0.37) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL5148633 | 0.83 | CA1 (0.39) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL9122699 | 0.82 | CA1 (0.40) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL9122704 | 0.82 | CA1 (0.40) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL2877170 | 0.81 | GAA (0.43) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL2877172 | 0.81 | GAA (0.43) | NPC1RAB9ASMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050267092-A1 | Novel cephalosporin compounds and process for preparing the same | LG LEF SCIENCES LTD. (KR) | 2005-12-01 | — | — | US | disclosed |
| US-5389626-A | 3-aryloxmethyl-cephalosporin derivatives, and their medical use | SANKYO COMPANY, LIMITED (JP) | 1995-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267092-A1 | Novel cephalosporin compounds and process for preparing the same | PEPD, CTRC, CHLSN | NPC1 658/4885RAB9A 1419/4885SMN1; SMN2 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.