Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.65 |
| ▸ | PPARD | Q03181 | 12/20 | 0.65 |
| ▸ | PPARA | Q07869 | 11/20 | 0.65 |
| ▸ | ALB | P02768 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CPT1A | P50416 | 2/20 | 0.54 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | CPT2 | P23786 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351239 | 0.93 | PPARG (0.65) | PPARGPPARDPPARAALBSMN1; SMN2 | |
| SCHEMBL6357406 | 0.90 | CPT1A (0.54) | PPARGPPARDPPARAALBTP53 | |
| SCHEMBL6347350 | 0.89 | PPARG (0.74) | PPARGPPARDPPARAALBSMN1; SMN2 | |
| SCHEMBL6351726 | 0.87 | MAPT (0.50) | PPARGPPARDPPARAALBTP53 | |
| SCHEMBL6353192 | 0.85 | PPARG (0.62) | PPARGPPARDPPARAALBSMN1; SMN2 | |
| SCHEMBL6353169 | 0.85 | CPT1A (0.53) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL6712188 | 0.84 | MAPT (0.57) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL6814072 | 0.84 | PPARG (0.49) | PPARGPPARDPPARAALBCPT1A | |
| SCHEMBL6346544 | 0.83 | PPARG (0.66) | PPARGPPARDPPARAALBSMN1; SMN2 | |
| SCHEMBL15788196 | 0.83 | MAPT (0.61) | PPARGPPARDPPARATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | PPARG 3572/4885PPARD 2519/4885PPARA 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.