SCHEMBL6360254

SCHEMBL6360254

CCN1CC(=O)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.53
NPY5R Q15761 1/20 0.43
HSD17B3 P37058 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KCNN4 O15554 2/20 0.39
KCNA3 P22001 2/20 0.39
ALDH1A1 P00352 8/20 0.39
HPGD P15428 2/20 0.39
CASP1 P29466 1/20 0.39
MPI P34949 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 2/20 0.38
CES1 P23141 2/20 0.38
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712077 0.81 ALDH1A1 (0.53) NOTUMMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL28680953 0.80 NOTUM (0.49) NOTUMMEN1KMT2AKCNN4KCNA3
SCHEMBL18134861 0.76 HTT (0.46) MEN1KMT2AALDH1A1HPGDCASP1
SCHEMBL6360056 0.76 ALDH1A1 (0.41) MEN1KMT2AALDH1A1HPGDCASP1
SCHEMBL30776885 0.74 NOTUM (0.58) NOTUMMEN1KMT2AKCNN4KCNA3
SCHEMBL6366299 0.74 NOTUM (0.58) NOTUMMEN1KMT2AKCNN4KCNA3
SCHEMBL12101846 0.73 NOTUM (0.30) NOTUM
SCHEMBL6362589 0.73 CES1 (0.44) ALDH1A1HPGDCASP1MPICACNA1B
SCHEMBL5711999 0.72 NOTUM (0.70) NOTUMMEN1KMT2AKCNN4KCNA3
SCHEMBL21300793 0.70 HSD17B3 (0.44) NPY5RHSD17B3MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109662961-A For improving the method and composition of cognitive function 约翰斯霍普金斯大学 2019-04-23 CN disclosed
CN-109662964-A For improving the method and composition of cognitive function 约翰斯.霍普金斯大学 2019-04-23 CN disclosed
CN-107243007-A Improve the method and composition of cognitive function 约翰斯.霍普金斯大学 2017-10-13 CN disclosed
EP-1317013-B1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEM CORP (JP) 2017-03-15 EP disclosed
EP-2037323-B1 Photosensitive compositions FUJIFILM CORP (JP) 2014-12-10 EP disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
EP-2207062-B1 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORP (JP) 2012-09-12 EP disclosed
EP-2037323-A2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM Corporation (JP) 2009-03-18 EP disclosed
US-20090023085-A1 Photosensitive Compositions, Curable Compositions, Novel Compounds, Photopolymerizable Compositions, Color Filters, and Planographic Printing Plate Precursors FUJIFILM CORPORATION (JP) 2009-01-22 US disclosed
US-20090023085-A1 Photosensitive Compositions, Curable Compositions, Novel Compounds, Photopolymerizable Compositions, Color Filters, and Planographic Printing Plate Precursors FUJIFILM CORPORATION (JP) 2009-01-22 US disclosed
US-6942948-B2 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-13 US disclosed
US-20030165733-A1 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2003-09-04 US disclosed
EP-1317013-A1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2003-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023085-A1 Photosensitive Compositions, Curable Compositions, Novel Compounds, Photopolymerizable Compositions, Color Filters, and Planographic Printing Plate Precursors RB1, MC1R, TYR NOTUM 4764/4885NPY5R 1891/4885HSD17B3 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.