Balazipone

Balazipone

SCHEMBL636109

CC(=O)C(=Cc1cccc(C#N)c1)C(C)=O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.55
CD274 Q9NZQ7 1/20 0.55
FBP1 P09467 3/20 0.54
GLO1 Q04760 1/20 0.53
P4HB P07237 9/20 0.48
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
GRIN2D O15399 2/20 0.45
GRIN3B O60391 2/20 0.45
GRIN1 Q05586 2/20 0.45
GRIN2A Q12879 2/20 0.45
GRIN2B Q13224 2/20 0.45
GRIN2C Q14957 2/20 0.45
GRIN3A Q8TCU5 2/20 0.45
GAA P10253 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9475845 0.92 PDCD1 (0.51) PDCD1CD274FBP1GLO1P4HB
SCHEMBL9475839 0.92 PDCD1 (0.51) PDCD1CD274FBP1GLO1P4HB
SCHEMBL6947909 0.88 PDCD1 (0.54) PDCD1CD274FBP1GLO1P4HB
SCHEMBL6947906 0.88 PDCD1 (0.54) PDCD1CD274FBP1GLO1P4HB
SCHEMBL10375509 0.85 PDCD1 (0.71) PDCD1CD274FBP1GLO1KDM4E
SCHEMBL10848993 0.85 PDCD1 (0.71) PDCD1CD274FBP1GLO1KDM4E
SCHEMBL8028834 0.84 PDCD1 (0.59) PDCD1CD274FBP1P4HBGRIN2D
SCHEMBL6981746 0.83 AKR1C3 (0.59) PDCD1CD274FBP1P4HBMAOA
SCHEMBL3115027 0.83 AKR1C3 (0.59) PDCD1CD274FBP1P4HBMAOA
SCHEMBL28372992 0.83 AKR1C3 (0.59) PDCD1CD274FBP1P4HBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
CN-1230891-A Lectin compositions and uses thereof ALIZYME THERAPEUTICS LTD (GB) 1999-10-06 CN claimed
US-5962024-A DRUG RELEASE CONTROLLING AGENT CONSISTS SUBSTANTIALLY OF A PH-SENSITIVE ENTERIC POLYMER. ORION-YHTYMA OY (FI) 1999-10-05 US claimed
EP-0942741-A1 LECTIN COMPOSITIONS AND USES THEREOF Alizyme Therapeutics Limited (GB) 1999-09-22 EP claimed
WO-1997049420-A1 LECTIN COMPOSITIONS AND USES THEREOF ALIZYME THERAPEUTICS LIMITED (GB) 1997-12-31 WO claimed
EP-0357403-B1 Substituted beta-diketones ORION YHTYMAE OY (FI) 1994-12-14 EP claimed
US-5292771-A Treating inflammatory bowel disease ORION-YHTYMA OY (FI) 1994-03-08 US claimed
US-5288750-A Antiulcer agents for gastrointestinal disorders ORION-YHTYMA OY (FI) 1994-02-22 US claimed
EP-0440324-A2 Substituted beta-diketones and their use ORION-YHTYMÀ„ OY (FI) 1991-08-07 EP claimed
WO-1990002724-A1 SUBSTITUTED β-DIKETONES Orion-Yhtymä Oy (FI) 1990-03-22 WO claimed
EP-0357403-A2 Substituted beta-diketones ORION-YHTYMÀ„ OY (FI) 1990-03-07 EP claimed