Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.81 |
| ▸ | CNR2 | P34972 | 3/20 | 0.77 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | GMNN | O75496 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indomethacin Morpholinylamide SCHEMBL8314320 | 0.87 | CNR2 (1.00) | PTGS2CNR2PKMMEN1GMNN | |
| Indomethacin Morpholinylamide SCHEMBL29358919 | 0.87 | CNR2 (1.00) | PTGS2CNR2PKMMEN1GMNN | |
| SCHEMBL6361108 | 0.87 | CNR2 (0.75) | PTGS2CNR2PKMMEN1GMNN | |
| SCHEMBL30077218 | 0.86 | PTGS2 (0.91) | PTGS2CNR2PKMMEN1CYP1A2 | |
| SCHEMBL12742120 | 0.86 | PTGS2 (0.91) | PTGS2CNR2PKMMEN1CYP1A2 | |
| SCHEMBL11174704 | 0.84 | PTGS2 (0.85) | PTGS2CNR2PKMMEN1CYP1A2 | |
| SCHEMBL13813542 | 0.84 | PTGS2 (1.00) | PTGS2CNR2PKMMEN1CYP1A2 | |
| SCHEMBL1394516 | 0.84 | PTGS2 (0.81) | PTGS2CNR2PKMMEN1CYP1A2 | |
| SCHEMBL19376389 | 0.83 | PTGS2 (0.84) | PTGS2CNR2PKMMEN1CYP1A2 | |
| SCHEMBL16008849 | 0.83 | PTGS2 (0.84) | PTGS2CNR2PKMMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004118-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compounds | JILANI JAMAL A (JO) | 2005-01-06 | — | — | US | claimed |
| US-20030060465-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compounds | SPECIALIZED PHARMACEUTICAL RESEARCH LTD. CO. (JO) | 2003-03-27 | — | — | US | claimed |
| EP-1231209-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compound | Specialized Pharmaceutical Research Ltd. Co. (JO) | 2002-08-14 | — | — | EP | claimed |
| US-20050004118-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compounds | JILANI JAMAL A (JO) | 2005-01-06 | — | — | US | disclosed |
| US-20030060465-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compounds | SPECIALIZED PHARMACEUTICAL RESEARCH LTD. CO. (JO) | 2003-03-27 | — | — | US | disclosed |
| EP-1231209-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compound | Specialized Pharmaceutical Research Ltd. Co. (JO) | 2002-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004118-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compounds | HCAR2, NONO, ALOX15 | PTGS2 14/4885CNR2 73/4885PKM 3783/4885 |
| US-20030060465-A1 | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compounds | NONO, CCNO, HCAR2 | PTGS2 14/4885CNR2 147/4885PKM 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.