Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6360922 | 0.99 | P2RX7 (0.55) | P2RX7DRD1DRD4DRD5SLC6A2 | |
| SCHEMBL6359746 | 0.90 | TSHR (0.49) | P2RX7SLC6A2SLC6A4TRPA1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6356625 | 0.89 | KDM4E (0.49) | P2RX7SLC6A2SLC6A4TRPA1SIGMAR1 | |
| SCHEMBL6357269 | 0.81 | P2RX7 (0.67) | P2RX7SLC6A2SLC6A4TRPA1SIGMAR1 | |
| SCHEMBL6356216 | 0.78 | P2RX7 (0.70) | P2RX7SLC6A2SLC6A4TRPA1SIGMAR1 | |
| SCHEMBL5815997 | 0.78 | P2RX7 (0.74) | P2RX7TRPA1SIGMAR1 | |
| SCHEMBL6354503 | 0.77 | P2RX7 (0.60) | P2RX7SLC6A2SLC6A4TRPA1SIGMAR1 | |
| SCHEMBL6361761 | 0.77 | DRD1 (0.53) | P2RX7DRD1DRD4DRD5CYP2A13 | |
| SCHEMBL6362688 | 0.76 | P2RX7 (0.59) | P2RX7SLC6A2SLC6A4TRPA1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6359006 | 0.76 | DRD1 (0.53) | P2RX7DRD1DRD4DRD5CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | claimed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | TFAM, CYP11B2, CYP11B1 | P2RX7 448/4885DRD1 1257/4885DRD4 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.