Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341175 | 0.84 | ALDH1A1 (0.46) | LMNAALDH1A1SMN1; SMN2RAB9ACYP17A1 | |
| SCHEMBL14965544 | 0.81 | ALDH1A1 (0.52) | LMNAALDH1A1SMN1; SMN2RAB9ACYP17A1 | |
| SCHEMBL2368808 | 0.74 | LMNA (0.55) | LMNAALDH1A1SMN1; SMN2RAB9ACYP17A1 | |
| SCHEMBL2368929 | 0.73 | LMNA (0.61) | LMNAALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL2368780 | 0.73 | ALDH1A1 (0.40) | LMNAALDH1A1SMN1; SMN2RAB9ACYP17A1 | |
| SCHEMBL27094473 | 0.72 | ALDH1A1 (0.49) | LMNAALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL7215179 | 0.69 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL13527777 | 0.69 | SMN1; SMN2 (0.68) | LMNAALDH1A1SMN1; SMN2RAB9ACYP17A1 | |
| SCHEMBL16806037 | 0.66 | MAPK14 (0.45) | CYP17A1MAPTL3MBTL1MAPK14 | |
| SCHEMBL30341183 | 0.66 | NPC1 (0.47) | LMNAALDH1A1SMN1; SMN2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | LMNA 1126/4885ALDH1A1 247/4885SMN1; SMN2 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.