Eclazolast

Eclazolast

SCHEMBL636302

CCOCCOC(=O)c1nc2cc(Cl)ccc2o1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 3/20 0.43
ANO1 Q5XXA6 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
XDH P47989 1/20 0.43
TP53 P04637 2/20 0.42
MAOB P27338 1/20 0.42
POLB P06746 2/20 0.40
CASP3 P42574 2/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
AGPAT2 O15120 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10829015 0.89 MAOB (0.52) MEN1KMT2AMAPTANO1NPSR1
SCHEMBL11197714 0.84 KMT2A (0.51) MEN1KMT2AMAPTNPSR1XDH
SCHEMBL11347687 0.83 PARP3 (0.51) MEN1KMT2AMAPTNPSR1XDH
SCHEMBL11170471 0.82 RAB9A (0.48) KMT2AMAPTNPSR1XDHTP53
SCHEMBL11161951 0.81 DAGLA (0.51) MEN1KMT2AMAPTXDHPOLB
SCHEMBL11077235 0.81 TP53 (0.46) MEN1KMT2AMAPTANO1NPSR1
SCHEMBL11166473 0.79 MAPT (0.47) MAPTXDHTP53POLBALOX15
SCHEMBL11163100 0.79 HTT (0.42) MEN1KMT2AMAPTTP53MAOB
SCHEMBL10829024 0.79 MAPT (0.56) MEN1KMT2AMAPTANO1NPSR1
SCHEMBL10477441 0.77 CASP3 (0.43) MEN1KMT2AMAPTANO1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119004017-A Method and system for intelligently regulating and controlling thallus structure for edible fungus strain production 汉中聚农源农业科技有限公司 2024-11-22 CN claimed
CN-118777308-A Method and system for plate shape characterization and defect analysis judgment after steel plate quenching 陈俊康 2024-10-15 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-0327052-A2 Use of quinoline derivatives for making a medicament effective in the prevention and treatment of ulcers RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-08-09 EP claimed
US-4831040-A (IMIDAZOLO-, THIAZOLO-, OXAZOLO-)(4,5-H)-QUINOLINE RORER PHARMACEUTICAL CORPORATION (US) 1989-05-16 US claimed
US-4620010-A Process for preparing carboalkoxy substituted benzoxazole compounds USV PHARMACEUTICAL CORP. (US) 1986-10-28 US claimed
EP-0039919-B1 BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES WITH ANTI-ALLERGIC ACTIVITY USV PHARMACEUTICAL CORPORATION (US) 1983-12-28 EP claimed
EP-0039919-A1 Benzoxazole and benzothiazole derivatives with anti-allergic activity USV PHARMACEUTICAL CORPORATION (US) 1981-11-18 EP claimed
US-4298742-A ANTIALLERGENS USV PHARMACEUTICAL CORPORATION (US) 1981-11-03 US claimed