Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829015 | 0.82 | MAOB (0.52) | CASP3MAPTNPSR1SENP7LMNA | |
| SCHEMBL11077232 | 0.80 | CASP3 (0.44) | CASP3MAPTNPSR1SENP7LMNA | |
| SCHEMBL10829024 | 0.78 | MAPT (0.56) | CASP3MAPTNPSR1SENP7LMNA | |
| Eclazolast SCHEMBL636302 | 0.77 | MEN1 (0.46) | CASP3MAPTNPSR1SENP7LMNA | |
| SCHEMBL5095572 | 0.75 | MEN1 (0.51) | CASP3MAPTNPSR1SENP7LMNA | |
| SCHEMBL27654631 | 0.74 | MAPT (0.58) | CASP3MAPTSENP7LMNAFFAR2 | |
| SCHEMBL11197714 | 0.74 | KMT2A (0.51) | MAPTNPSR1LMNAALDH1A1MEN1 | |
| SCHEMBL5517471 | 0.73 | MAPT (0.42) | CASP3MAPTNPSR1SENP7LMNA | |
| SCHEMBL11347687 | 0.73 | PARP3 (0.51) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL4051005 | 0.73 | MAPT (0.42) | CASP3MAPTNPSR1SENP7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327052-A2 | Use of quinoline derivatives for making a medicament effective in the prevention and treatment of ulcers | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-08-09 | — | — | EP | claimed |
| US-4831040-A | (IMIDAZOLO-, THIAZOLO-, OXAZOLO-)(4,5-H)-QUINOLINE | RORER PHARMACEUTICAL CORPORATION (US) | 1989-05-16 | — | — | US | claimed |
| EP-0327052-A2 | Use of quinoline derivatives for making a medicament effective in the prevention and treatment of ulcers | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-08-09 | — | — | EP | disclosed |
| US-4831040-A | (IMIDAZOLO-, THIAZOLO-, OXAZOLO-)(4,5-H)-QUINOLINE | RORER PHARMACEUTICAL CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0039919-B1 | BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES WITH ANTI-ALLERGIC ACTIVITY | USV PHARMACEUTICAL CORPORATION (US) | 1983-12-28 | — | — | EP | disclosed |
| EP-0039919-A1 | Benzoxazole and benzothiazole derivatives with anti-allergic activity | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-18 | — | — | EP | disclosed |
| US-4298742-A | ANTIALLERGENS | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |