SCHEMBL6363338

SCHEMBL6363338

CCC(C)(C)C(=O)Nc1cccc2cccc(S(=O)(=O)O)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
POLB P06746 1/20 0.52
TTR P02766 1/20 0.51
FABP4 P15090 1/20 0.51
CCNA2 P20248 1/20 0.51
CDK2 P24941 1/20 0.51
MAPK14 Q16539 1/20 0.51
NR4A1 P22736 1/20 0.50
CD40 P25942 3/20 0.48
CD40LG P29965 3/20 0.48
CASP6 P55212 1/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RIPK1 Q13546 4/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CNR2 P34972 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6362788 0.86 LMNA (0.49) LMNAPOLBTTRFABP4CCNA2
SCHEMBL6362837 0.84 LMNA (0.55) LMNAPOLBALDH1A1GAATHRB
SCHEMBL11759224 0.80 TTR (0.59) LMNATTRFABP4CCNA2CDK2
SCHEMBL26885009 0.77 TTR (0.56) LMNAPOLBTTRFABP4CCNA2
SCHEMBL27459951 0.77 TTR (0.59) LMNAPOLBTTRFABP4CCNA2
SCHEMBL12863541 0.76 POLB (0.58) LMNAPOLBALDH1A1GAARIPK1
SCHEMBL23178061 0.75 TTR (0.64) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL5879414 0.75 LMNA (0.65) LMNAPOLBALDH1A1GAATHRB
SCHEMBL18768617 0.74 TTR (0.56) LMNAPOLBTTRFABP4CCNA2
SCHEMBL6242038 0.74 CD40 (0.61) TTRFABP4CCNA2CDK2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178271-B2 Polymer having a sulfonic group or a sulfonate group and an amide group and method of producing same CANON KABUSHIKI KAISHA (JP) 2012-05-15 US disclosed
US-20100233610-A1 POLYMER HAVING A SULFONIC GROUP OR A SULFONATE GROUP AND AN AMIDE GROUP AND METHOD OF PRODUCING SAME CANON KABUSHIKI KAISHA (JP) 2010-09-16 US disclosed
US-7795363-B2 Polymer having a sulfonic group or a sulfonate group and an amide group and method of producing same CANON KABUSHIKI KAISHA (JP) 2010-09-14 US disclosed
US-20100121023-A1 POLYMER HAVING A SULFONIC GROUP OR A SULFONATE GROUP AND AN AMIDE GROUP AND METHOD OF PRODUCING SAME CANON KABUSHIKI KAISHA (JP) 2010-05-13 US disclosed
US-7638194-B2 Developer carrying member, and developing assembly CANON KABUSHIKI KAISHA (JP) 2009-12-29 US disclosed
US-7399568-B2 Acrylic amide-resin-coating layer is attached to a carrier core material in a stable manner and which has sufficient charging properties for a toner and excellent environmental stability CANON KABUSHIKI KAISHA (JP) 2008-07-15 US disclosed
US-20070059627-A1 Polymer having a sulfonic group or a sulfonate group and an amide group and method of producing same CANON KABUSHIKI KAISHA (JP) 2007-03-15 US disclosed