Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084418 | 0.95 | LMNA (0.60) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL19422608 | 0.81 | SMN1; SMN2 (0.55) | LMNAPOLBMEN1KMT2A | |
| SCHEMBL16256513 | 0.81 | POLB (0.56) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL30525296 | 0.81 | CETP (0.59) | LMNAPOLBL3MBTL1ALDH1A1HTT | |
| SCHEMBL10027976 | 0.81 | LMNA (0.59) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL12863541 | 0.80 | POLB (0.58) | LMNAPOLBRIPK1ALDH1A1GAA | |
| SCHEMBL16300542 | 0.80 | POLB (0.58) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL19422611 | 0.79 | POLB (0.57) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL12963094 | 0.79 | LMNA (0.57) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7207413 | 0.79 | LMNA (0.61) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006518402-A | — | — | 2006-08-10 | — | — | JP | claimed |
| EP-1592738-A2 | RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | claimed |
| WO-2004072168-A2 | RESIN COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | claimed |