SCHEMBL636339

SCHEMBL636339

C=C(C)C(=O)OC.C=C(CO)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
TSHR P16473 3/20 0.41
THRB P10828 1/20 0.34
TGFBR1 P36897 2/20 0.33
EGLN1 Q9GZT9 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TET2 Q6N021 4/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1897831 0.87 ALDH1A1 (0.68) ALDH1A1TSHRTHRBTGFBR1EGLN1
SCHEMBL2018843 0.87 ALDH1A1 (0.68) ALDH1A1TSHRTHRBTGFBR1EGLN1
Methacrylic Acid SCHEMBL3676604 0.85 ALDH1A1 (0.52) ALDH1A1TSHRTHRBTGFBR1EGLN1
Methacrylic Acid SCHEMBL17961024 0.85 ALDH1A1 (0.52) ALDH1A1TSHRTHRBTGFBR1EGLN1
SCHEMBL27809702 0.84 ALDH1A1 (0.58) ALDH1A1TSHRTHRBTGFBR1EGLN1
Itaconate SCHEMBL15419775 0.83 ALDH1A1 (0.62) ALDH1A1TSHRTHRBEGLN1ALOX15
Methacrylic Acid SCHEMBL28070047 0.83 ALDH1A1 (0.50) ALDH1A1TSHRTHRBTGFBR1EGLN1
SCHEMBL667786 0.83 ALDH1A1 (0.62) ALDH1A1TSHRTHRBEGLN1ALOX15
Methacrylic Acid SCHEMBL10387701 0.83 ALDH1A1 (0.68) ALDH1A1TSHRTHRBTGFBR1EGLN1
Methacrylic Acid SCHEMBL1291895 0.83 ALDH1A1 (0.68) ALDH1A1TSHRTHRBTGFBR1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9637729-B2 Cell and enzyme compositions for modulating bile acids, cholesterol and triglycerides UAS LABORATORIES LLC (US) 2017-05-02 US claimed
EP-3067056-A1 BACTERIAL COMPOSITIONS FOR PROPHYLAXIS AND TREATMENT OF DEGENERATIVE DISEASE UAS Laboratories LLC (US) 2016-09-14 EP claimed
EP-2419114-B1 BACTERIAL COMPOSITIONS FOR PROPHYLAXIS AND TREATMENT OF DEGENERATIVE DISEASE UAS LAB LLC (US) 2016-04-20 EP claimed
US-20150166975-A1 Cell And Enzyme Compositions For Modulating Bile Acids, Cholesterol and Triglycerides UAS LABORATORIES LLC (US) 2015-06-18 US claimed
US-8932578-B2 Cell and enzyme compositions for modulating ale acids, cholesterol and triglycerides UAS LABORATORIES LLC (US) 2015-01-13 US claimed
EP-2419114-A1 BACTERIAL COMPOSITIONS FOR PROPHYLAXIS AND TREATMENT OF DEGENERATIVE DISEASE Micropharma Limited (CA) 2012-02-22 EP claimed
JP-2011525116-A 2011-09-15 JP claimed
US-7939061-B2 Cell and enzyme compositions for modulating bile acids, cholesterol and triglycerides MICROPHARMA LIMITED (CA) 2011-05-10 US claimed
EP-2300604-A1 NITRIC OXIDE COMPOSITIONS AND DEVICES AND METHODS FOR COSMESIS Micropharma Limited (CA) 2011-03-30 EP claimed
EP-2300603-A1 NITRIC OXIDE DEVICE AND METHOD FOR WOUND HEALING, TREATMENT OF DERMATOLOGICAL DISORDERS AND MICROBIAL INFECTIONS Micropharma Limited (CA) 2011-03-30 EP claimed
WO-2010124387-A1 BACTERIAL COMPOSITIONS FOR PROPHYLAXIS AND TREATMENT OF DEGENERATIVE DISEASE MICROPHARMA LIMITED (CA) 2010-11-04 WO claimed
US-20100074933-A1 Cell And Enzyme Compositions For Modulating Bile Acids, Cholesterol and Triglycerides CHR. HANSEN A/S (DK) 2010-03-25 US claimed
WO-2009155689-A1 NITRIC OXIDE DEVICE AND METHOD FOR WOUND HEALING, TREATMENT OF DERMATOLOGICAL DISORDERS AND MICROBIAL INFECTIONS MICROPHARMA LIMITED (CA) 2009-12-30 WO claimed
WO-2009155690-A1 NITRIC OXIDE COMPOSITIONS AND DEVICES AND METHODS FOR COSMESIS MICROPHARMA LIMITED (CA) 2009-12-30 WO claimed
WO-2024108164-A1 ENZYMATICALLY PRODUCED BIOPESTICIDES ZYMTRONIX CATALYTIC SYSTEMS, INC. (US) 2024-05-23 WO disclosed
CN-116794759-A Optical laminate and image display device 富士胶片株式会社 2023-09-22 CN disclosed
US-20230090705-A1 RECOMBINANT BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH METHIONINE METABOLISM AND METHODS OF USE THEREOF SYNLOGIC OPERATING COMPANY, INC. 2023-03-23 US disclosed
US-20070116671-A1 Cell and enzyme compositions for modulating bile acids, cholesterol and triglycerides CHR. HANSEN A/S (DK) 2007-05-24 US disclosed
EP-1639108-A2 CELL AND ENZYME COMPOSITIONS FOR MODULATING BILE ACIDS, CHOLESTEROL AND TRIGLYCERIDES McGILL UNIVERSITY (CA) 2006-03-29 EP disclosed
WO-2004076657-A2 CELL AND ENZYME COMPOSITIONS FOR MODULATING BILE ACIDS, CHOLESTEROL AND TRIGLYCERIDES MCGILL UNIVERSITY (CA) 2004-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074933-A1 Cell And Enzyme Compositions For Modulating Bile Acids, Cholesterol and Triglycerides CEL, CETP, PNLIP ALDH1A1 1394/4885TSHR 1287/4885THRB 887/4885
US-20070116671-A1 Cell and enzyme compositions for modulating bile acids, cholesterol and triglycerides CEL, CETP, PNLIP ALDH1A1 1394/4885TSHR 1287/4885THRB 887/4885
US-20150166975-A1 Cell And Enzyme Compositions For Modulating Bile Acids, Cholesterol and Triglycerides CEL, CETP, PNLIP ALDH1A1 1394/4885TSHR 1287/4885THRB 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.