Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 13/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364711 | 1.00 | STS (0.46) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL8206494 | 0.83 | STS (0.48) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL8206491 | 0.83 | STS (0.48) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL9627672 | 0.82 | LMNA (0.55) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL8938753 | 0.80 | LMNA (0.51) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL9628223 | 0.80 | LMNA (0.57) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL9627648 | 0.78 | MAPT (0.59) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL514373 | 0.77 | ESR1 (0.53) | STSCYP2C9ESR1ESR2CYP3A4 | |
| SCHEMBL29500480 | 0.77 | ESR1 (0.53) | STSCYP2C9ESR1ESR2CYP3A4 | |
| SCHEMBL8959369 | 0.77 | ESR1 (0.53) | STSCYP2C9ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061868-A1 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | STERIX LIMITED (GB) | 2002-05-23 | — | — | US | claimed |
| US-6841548-B2 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | SCHERING AG (DE) | 2005-01-11 | — | — | US | disclosed |
| US-6569844-B1 | Hormonal contraception and hormon replacement therapy with low hepatic estrogenity | JENAPHARM GMBH & CO., KG (DE) | 2003-05-27 | — | — | US | disclosed |
| US-20020061868-A1 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | STERIX LIMITED (GB) | 2002-05-23 | — | — | US | disclosed |
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061868-A1 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | ESRRA, ESR2, CYP19A1 | STS 124/4885ABCC4 2078/4885ABCC1 819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.