Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 3/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125433 | 0.89 | NQO1 (0.38) | NQO1HSD17B3MAPTRXFP1PRNP | |
| SCHEMBL5118767 | 0.88 | HSD17B3 (0.37) | NQO1HSD17B3MAPTRXFP1PRNP | |
| SCHEMBL5125229 | 0.88 | PRNP (0.42) | NQO1HSD17B3MAPTPDE2ARXFP1 | |
| SCHEMBL5114488 | 0.86 | NQO1 (0.38) | NQO1RXFP1PRNPKDM4EALDH1A1 | |
| SCHEMBL5342546 | 0.83 | NQO1 (0.49) | NQO1HSD17B3MAPTPDE2ARXFP1 | |
| SCHEMBL5117858 | 0.82 | NQO1 (0.46) | NQO1HSD17B3MAPTKDM4EALDH1A1 | |
| SCHEMBL5124909 | 0.81 | NQO1 (0.37) | NQO1MAPTRXFP1PRNPKDM4E | |
| SCHEMBL5126126 | 0.80 | NQO1 (0.48) | NQO1MAPTRXFP1KDM4EALDH1A1 | |
| SCHEMBL5120361 | 0.79 | NQO1 (0.53) | NQO1MAPTRXFP1NPC1KDM4E | |
| SCHEMBL5112347 | 0.79 | NQO1 (0.47) | NQO1MAPTRXFP1PRNPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075388-A1 | Products of condensations of hydroxycoumarin derivatives with aromatic and aliphatic dialdehydes, their preparation and antiviral action thereof | PLIVA-ISTRAZIVACKI INSTITUTE D.O.O. (HR) | 2005-04-07 | — | — | US | disclosed |
| EP-1448543-A1 | PRODUCTS OF CONDENSATIONS OF HYDROXYCOUMARIN DERIVATIVES WITH AROMATIC AND ALIPHATIC DIALDEHYDES, THEIR PREPARATION AND ANTIVIRAL ACTION THEREOF | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003029237-A1 | PRODUCTS OF CONDENSATIONS OF HYDROXYCOUMARIN DERIVATIVES WITH AROMATIC AND ALIPHATIC DIALDEHYDES, THEIR PREPARATION AND ANTIVIRAL ACTION THEREOF | PLIVA, FARMACEUTSKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075388-A1 | Products of condensations of hydroxycoumarin derivatives with aromatic and aliphatic dialdehydes, their preparation and antiviral action thereof | MAVS, EIF2AK2, DDX17 | NQO1 199/4885HSD17B3 733/4885MAPT 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.