Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 11/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118520 | 0.91 | CSNK2A2 (0.38) | NQO1CSNK2A2CSNK2BCSNK2A1TSHR | |
| SCHEMBL5120322 | 0.87 | NQO1 (0.46) | NQO1TSHRHSD17B3KDM4EALDH1A1 | |
| SCHEMBL5126126 | 0.86 | NQO1 (0.48) | NQO1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL5124909 | 0.85 | NQO1 (0.37) | NQO1MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL5125229 | 0.84 | PRNP (0.42) | NQO1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL5341857 | 0.84 | NQO1 (0.49) | NQO1CSNK2A2CSNK2BCSNK2A1HSD17B3 | |
| SCHEMBL14172459 | 0.84 | NQO1 (0.49) | NQO1HSD17B3KDM4EALDH1A1HPGD | |
| SCHEMBL5125433 | 0.83 | NQO1 (0.38) | NQO1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL5120361 | 0.82 | NQO1 (0.53) | NQO1CSNK2A2CSNK2BCSNK2A1TSHR | |
| SCHEMBL5112347 | 0.82 | NQO1 (0.47) | NQO1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384975-B2 | Substituted furochromenes, preparation thereof and their antiinflammatory action | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2008-06-10 | — | — | US | disclosed |
| US-20060148889-A1 | Substituted furochromenes, preparation thereof and their antiinflammatory action | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148889-A1 | Substituted furochromenes, preparation thereof and their antiinflammatory action | CYP11B2, CYP11B1, LTC4S | NQO1 60/4885CSNK2A2 886/4885CSNK2B 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.