SCHEMBL636711

SCHEMBL636711

C=CCN(CC=C)CCCN(CCCN(CC=C)CC=C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2699253 0.81 ALDH1A1 (0.35) KDM4EALDH1A1KMT2ATDP1
SCHEMBL6527091 0.78 OPRK1 (0.35) KDM4EALDH1A1KMT2ATDP1
SCHEMBL213436 0.75 ALDH1A1 (0.35) KDM4EALDH1A1KMT2ATDP1
SCHEMBL11069847 0.75
SCHEMBL5485335 0.75 ALDH1A1 (0.41) KDM4EALDH1A1KMT2ATDP1
SCHEMBL12464312 0.74 MEN1 (0.32) KMT2A
SCHEMBL1137481 0.73 MEN1 (0.33) KMT2A
SCHEMBL3655351 0.73 KDM4E (0.33) KDM4EALDH1A1KMT2ATDP1
SCHEMBL3060057 0.73 KDM4E (0.33) KDM4EALDH1A1KMT2ATDP1
SCHEMBL6943640 0.73 KDM4E (0.33) KDM4EALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518247-B2 Fabric care compositions comprising organosiloxane polymers THE PROCTER & GAMBLE COMPANY (US) 2016-12-13 US disclosed
US-9469829-B2 Fabric care compositions comprising organosiloxane polymers THE PROCTER & GAMBLE COMPANY (US) 2016-10-18 US disclosed
EP-2419498-B1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS PROCTER & GAMBLE (US) 2016-08-10 EP disclosed
US-20150291915-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS PROCTER & GAMBLE (US) 2015-10-15 US disclosed
US-20150275140-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS PROCTER & GAMBLE (US) 2015-10-01 US disclosed
US-9085749-B2 Fabric care compositions comprising organosiloxane polymers THE PROCTER & GAMBLE COMPANY (US) 2015-07-21 US disclosed
US-20140047648-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2014-02-20 US disclosed
US-8598108-B2 Fabric care compositions comprising organosiloxane polymers THE PROCTER & GAMBLE COMPANY (US) 2013-12-03 US disclosed
EP-2552999-A1 METHODS OF EMULSIFYING ORGANOSILOXANE POLYMERS The Procter & Gamble Company (US) 2013-02-06 EP disclosed
US-20120302488-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS PANANDIKER RAJAN KESHAV (US) 2012-11-29 US disclosed
US-8263543-B2 Fabric care compositions comprising organosiloxane polymers THE PROCTER & GAMBLE COMPANY (US) 2012-09-11 US disclosed
EP-2419498-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS The Procter & Gamble Company (US) 2012-02-22 EP disclosed
WO-2011123728-A1 METHODS OF EMULSIFYING ORGANOSILOXANE POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2011-10-06 WO disclosed
US-20110245123-A1 METHODS OF EMULSIFYING ORGANOSILOXANE POLYMERS THE PROCTER & GAMBLE COMPANY 2011-10-06 US disclosed
WO-2010120863-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2010-10-21 WO disclosed
US-20100267601-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245123-A1 METHODS OF EMULSIFYING ORGANOSILOXANE POLYMERS PIGS, STS, SQLE KDM4E 4343/4885ALDH1A1 3129/4885KMT2A 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.