Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 2/20 | 0.34 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 8/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319973 | 0.87 | METAP2 (0.36) | METAP2METAP1RNPEPBHMTBHMT2 | |
| Leucine SCHEMBL16348668 | 0.86 | SLC7A5 (0.40) | METAP2METAP1BHMTBHMT2FOLH1 | |
| Alanine SCHEMBL1409244 | 0.84 | BHMT (0.32) | METAP2METAP1RNPEPBHMTBHMT2 | |
| Serine SCHEMBL5577056 | 0.83 | RNPEP (0.37) | METAP2METAP1RNPEPBHMTBHMT2 | |
| Leucine SCHEMBL15323685 | 0.83 | SLC7A5 (0.47) | METAP2METAP1RNPEPBHMTBHMT2 | |
| Methionine SCHEMBL4361132 | 0.81 | BHMT (0.46) | RNPEPBHMTBHMT2 | |
| Racemethionine SCHEMBL4361129 | 0.81 | BHMT (0.46) | RNPEPBHMTBHMT2 | |
| SCHEMBL5707660 | 0.81 | METAP2 (0.40) | METAP2METAP1RNPEPBHMTBHMT2 | |
| SCHEMBL16876652 | 0.81 | GSR (0.38) | — | |
| Racemethionine SCHEMBL23924294 | 0.81 | BHMT (0.50) | RNPEPBHMTBHMT2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933145-B1 | Materials and methods for delivery and expression of heterologous DNA in vertebrate cells | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-08-23 | — | — | US | disclosed |
| US-20050014263-A1 | Materials and methods for delivery and expression of heterologous DNA in vertebrate cells | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2005-01-20 | — | — | US | disclosed |
| EP-1307572-A2 | MATERIALS AND METHODS FOR DELIVERY AND EXPRESSION OF HETEROLOGOUS DNA IN VERTEBRATE CELLS | University Of Florida Research Foundation, Inc. (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012526-A2 | MATERIALS AND METHODS FOR DELIVERY AND EXPRESSION OF HETEROLOGOUS DNA IN VERTEBRATE CELLS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2002-02-14 | — | — | WO | disclosed |