Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.58 |
| ▸ | HTR5A | P47898 | 8/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28066351 | 0.76 | HTR5A (0.68) | HTR5AHTR7 | |
| SCHEMBL6367272 | 0.73 | PARP1 (1.00) | PARP1 | |
| SCHEMBL22944855 | 0.73 | HTR5A (0.67) | HTR5A | |
| SCHEMBL29133429 | 0.72 | HTR5A (0.52) | PARP1HTR5AHTR7 | |
| SCHEMBL6367194 | 0.72 | PARP1 (0.98) | PARP1 | |
| SCHEMBL30704377 | 0.71 | HTR5A (0.56) | HTR5AHTR7 | |
| SCHEMBL29133431 | 0.71 | HTR5A (0.56) | HTR5AHTR7 | |
| SCHEMBL6368050 | 0.70 | PARP1 (0.85) | PARP1HTR7 | |
| SCHEMBL6366828 | 0.70 | PARP1 (0.70) | PARP1HTR7 | |
| SCHEMBL6373163 | 0.70 | PARP1 (0.70) | PARP1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080096-A1 | Condensed heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080096-A1 | Condensed heterocyclic compounds | PARP1, PARP2, PARP3 | PARP1 1/4885HTR5A 1443/4885HTR7 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.