Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704377 | 0.81 | HTR5A (0.56) | HTR5AHTR7DRD2DRD4 | |
| SCHEMBL29133431 | 0.81 | HTR5A (0.56) | HTR5AHTR7DRD2DRD4 | |
| SCHEMBL30704344 | 0.79 | HTR5A (0.61) | HTR5AHTR1ADRD2HTR2ADRD1 | |
| SCHEMBL6404364 | 0.77 | PARP1 (0.51) | HTR5AHTR7GRIN2BPARP1 | |
| SCHEMBL30704343 | 0.74 | HTR5A (0.64) | HTR5AHTR1ADRD2HTR2ADRD1 | |
| SCHEMBL29133407 | 0.73 | DRD3 (0.59) | HTR1ADRD2HTR2ADRD4HTR2C | |
| SCHEMBL6367185 | 0.72 | PARP1 (0.58) | HTR5AHTR7PARP1 | |
| SCHEMBL10838310 | 0.72 | SIGMAR1 (0.63) | HTR7HTR1ADRD2HTR2AHTR2C | |
| Bromide SCHEMBL28066351 | 0.72 | HTR5A (0.68) | HTR5AHTR7HTR1A | |
| Hydrochloric Acid SCHEMBL10836549 | 0.72 | SIGMAR1 (0.62) | HTR7HTR1ADRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |