Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 7/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704377 | 1.00 | HTR5A (0.56) | HTR5ADRD2HTR7DRD4CA12 | |
| SCHEMBL29133429 | 0.81 | HTR5A (0.52) | HTR5ADRD2HTR7DRD4 | |
| SCHEMBL30704357 | 0.79 | HTR5A (0.64) | HTR5ADRD2 | |
| SCHEMBL29133409 | 0.79 | HTR5A (0.64) | HTR5ADRD2 | |
| Bromide SCHEMBL28066351 | 0.73 | HTR5A (0.68) | HTR5AHTR7 | |
| SCHEMBL6367185 | 0.71 | PARP1 (0.58) | HTR5AHTR7 | |
| SCHEMBL6404364 | 0.70 | PARP1 (0.51) | HTR5AHTR7 | |
| SCHEMBL22944855 | 0.70 | HTR5A (0.67) | HTR5A | |
| SCHEMBL29133438 | 0.68 | HTR5A (0.61) | HTR5ADRD2 | |
| SCHEMBL30704356 | 0.68 | HTR5A (0.61) | HTR5ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |