Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957117 | 0.91 | TDO2 (0.48) | TDO2ESR1MIFPTGER4PTGER3 | |
| SCHEMBL957118 | 0.91 | TDO2 (0.48) | TDO2ESR1MIFPTGER4PTGER3 | |
| SCHEMBL7937601 | 0.84 | MIF (0.53) | ESR1ESR2MIFPTGER4PTGER3 | |
| SCHEMBL7937596 | 0.84 | MIF (0.53) | ESR1ESR2MIFPTGER4PTGER3 | |
| SCHEMBL28552435 | 0.84 | ATG4B (0.48) | PTGER4PTGER3PTGER2KDM4EEGFR | |
| SCHEMBL955439 | 0.82 | ESR1 (0.46) | ESR1MIFKDM4EALDH1A1PPARA | |
| SCHEMBL955440 | 0.82 | ESR1 (0.46) | ESR1MIFKDM4EALDH1A1PPARA | |
| SCHEMBL1322604 | 0.82 | ESR1 (0.43) | ESR1ESR2PTGER4PTGER3PTGER2 | |
| SCHEMBL6367849 | 0.81 | PTGER4 (0.49) | ESR1ESR2PTGER4PTGER3PTGER2 | |
| SCHEMBL5178122 | 0.81 | PTGER4 (0.49) | ESR1ESR2PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050010068-A1 | Use of microencapsulated transition metal reagents for reactions in supercritical fluids | AVECIA LIMITED (GB) | 2005-01-13 | — | — | US | disclosed |
| EP-1453780-A1 | THE USE OF MICROENCAPSULATED TRANSITION METAL REAGENTS FOR REACTIONS IN SUPERCRITICAL FLUIDS | Avecia Limited (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048090-A1 | THE USE OF MICROENCAPSULATED TRANSITION METAL REAGENTS FOR REACTIONS IN SUPERCRITICAL FLUIDS | AVECIA LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010068-A1 | Use of microencapsulated transition metal reagents for reactions in supercritical fluids | HPSE, SIK1, SGK1 | TDO2 1491/4885ESR1 3170/4885ESR2 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.