SCHEMBL6368286

SCHEMBL6368286

COc1ccc(S(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.52
CA2 P00918 7/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
PARP1 P09874 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP2 Q9UGN5 1/20 0.45
PARP4 Q9UKK3 1/20 0.45
ACHE P22303 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LTA4H P09960 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP2A6 P11509 1/20 0.43
ESR2 Q92731 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7513563 0.98 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL11297957 0.98 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL7514704 0.98 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL357933 0.98 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL14124758 0.94 LTA4H (0.54) CA1CA2CA7CA9CA12
SCHEMBL14124827 0.94 ESR2 (0.54) CA1CA2CA7CA9CA12
SCHEMBL6326434 0.92 ESR2 (0.52) CA1CA2CA7CA9CA12
Diphenylmethanol SCHEMBL10871922 0.82 ACP3 (0.49) CES2CES1NPC1RAB9ASMN1; SMN2
SCHEMBL19593607 0.82 CES2 (0.31) CA1CA2CA7CA9CA12
SCHEMBL2236991 0.80 KMT2A (0.43) PARP10PARP2PARP4RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117142916-B Preparation method of allyl sulfone compound 安徽金桐精细化学有限公司 2024-10-11 CN claimed
CN-117326998-A Preparation method of sulfinic acid-based thiosulfate in aqueous phase 阜阳师范大学 2024-01-02 CN claimed
CN-117247369-A Preparation method of 2, 3-dihydrobenzo [ b ] thiophene 1, 1-dioxide derivative 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2023-12-19 CN claimed
CN-117142916-A Preparation method of allyl sulfone compound 安徽金桐精细化学有限公司 2023-12-01 CN claimed
US-10731000-B2 Poly(2,6-dimethyl-1,4-phenylene-oxide) derivatives with sulfonyl pendant groups and methods therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2020-08-04 US claimed
US-20190276603-A1 POLY(2,6-DIMETHYL-1,4-PHENYLENE-OXIDE) DERIVATIVES WITH SULFONYL PENDANT GROUPS AND METHODS THEREFOR GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-09-12 US claimed
US-20190055355-A1 POLY(2,6-DIMETHYL-1,4-PHENYLENE-OXIDE) DERIVATIVES WITH SULFONYL PENDANT GROUPS AND METHODS THEREFOR GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-02-21 US claimed
CN-109183393-A Graphene denatured conductive protein fibre and its preparation method and application 青岛大学 2019-01-11 CN claimed
CN-109183392-A Graphene denatured conductive cellulose fibre and its preparation method and application 青岛大学 2019-01-11 CN claimed
CN-109162088-A Graphene denatured conductive synthetic fibers and its preparation method and application 青岛大学 2019-01-08 CN claimed
CN-103641674-B Method for preparing diaryl sulfone ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2015-04-08 CN claimed
CN-103172479-B Preparation method for biaryl through palladium catalysis SHAOXING UNIVERSITY (CN) 2014-10-29 CN claimed
CN-104072323-A Symmetric biphenyl preparation method UNIV SHAOXING 2014-10-01 CN claimed
CN-103922976-A Asymmetric diaryl sulfone compound and preparation method thereof UNIV SHAOXING 2014-07-16 CN claimed
CN-103641674-A Method for preparing diaryl sulfone ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2014-03-19 CN claimed
CN-103172479-A Preparation method for biaryl through palladium catalysis UNIV SHAOXING 2013-06-26 CN claimed
CN-117142916-B Preparation method of allyl sulfone compound 安徽金桐精细化学有限公司 2024-10-11 CN disclosed
CN-117425984-A Flame-resistant electrode for lithium battery comprising quasi-solid electrolyte or solid electrolyte and method of manufacture 环球石墨烯集团公司 2024-01-19 CN disclosed
EP-0005251-A2 Process for the preparation of sulfinates of 4,4'-diaminobenzhydrol and of its substituted products, and copying paper containing these compounds BAYER AG (DE) 1979-11-14 EP disclosed
US-4120651-A Disulfones as peroxygen activators FMC CORPORATION (US) 1978-10-17 US disclosed